NDUFS2 Products
(NADH Dehydrogenase (Ubiquinone) Fe-S Protein 2, 49kDa (NADH-Coenzyme Q Reductase) (NDUFS2))
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The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
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Featured NDUFS2 Categories
NDUFS2 Antibodies
High quality antibodies with extensive validation data.
NDUFS2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NDUFS2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NDUFS2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), IF, ICC
Validations
- (4)
Cat. No.
ABIN2856976
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7160954
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7239254
Quantity
200 μL
Datasheet
Datasheet
Recommended NDUFS2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1144225
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1144226
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1144227
Quantity
96 tests
Datasheet
Datasheet
Recommended NDUFS2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312273
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312272
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2130795
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our NDUFS2 products
: "Targeting NAD+/PARP DNA Repair Pathway as a Novel Therapeutic Approach to SDHB-Mutated Cluster I Pheochromocytoma and Paraganglioma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 14, pp. 3423-3432, (2018) (PubMed).: "Granzyme B-induced mitochondrial ROS are required for apoptosis." in: Cell death and differentiation, Vol. 22, Issue 5, pp. 862-74, (2015) (PubMed).
: "Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease." in: American journal of human genetics, Vol. 84, Issue 6, pp. 718-27, (2009) (PubMed).
Synonyms and alternative names related to NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2 (Ndufs2), NADH:ubiquinone oxidoreductase core subunit S2 (Ndufs2), NADH:ubiquinone oxidoreductase core subunit S2 (NDUFS2), AL033311, CI-49Protein level used designations for NDUFS2
- CI-49kD
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
- NADH-coenzyme Q reductase
- NADH-ubiquinone oxidoreductase 49 kDa subunit
- complex I-49kD
- NADH-ubiquinone oxidoreductase NDUFS2 subunit
- complex 1, mitochondrial respiratory chain, 49-KD subunit
- complex I 49kDa subunit
- mitochondrial complex I subunit NDUFS2
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