NDUFS1 Products
(NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
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The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].
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Featured NDUFS1 Categories
NDUFS1 Antibodies
High quality antibodies with extensive validation data.
NDUFS1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NDUFS1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NDUFS1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7441598
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, ICC, IHC (p)
Validations
- (5)
Cat. No.
ABIN2856931
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN2856074
Quantity
100 μL
Datasheet
Datasheet
Recommended NDUFS1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958023
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5657176
Quantity
96 tests
Datasheet
Datasheet
Recommended NDUFS1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312270
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409485
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2727038
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our NDUFS1 products
: "Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy." in: Cell metabolism, Vol. 28, Issue 1, pp. 130-144.e7, (2019) (PubMed).: "Granzyme B-induced mitochondrial ROS are required for apoptosis." in: Cell death and differentiation, Vol. 22, Issue 5, pp. 862-74, (2015) (PubMed).
: "Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I." in: Molecular and cellular biology, Vol. 29, Issue 22, pp. 6059-73, (2009) (PubMed).
: "Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects." in: Journal of human genetics, Vol. 54, Issue 6, pp. 317-23, (2009) (PubMed).
Synonyms and alternative names related to NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1 (Ndufs1), NADH:ubiquinone oxidoreductase core subunit S1 (Ndufs1), NADH:ubiquinone oxidoreductase core subunit S1 (NDUFS1), 5830412M15Rik, 9930026A05Rik, CI-75k, CI-75Kd, PRO1304Protein level used designations for NDUFS1
- CI-75kD
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- complex I-75kD
- NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa
- complex I 75kDa subunit
- complex I, mitochondrial respiratory chain, 75-kD subunit
- mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit
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