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NDRG1 Products

(N-Myc Downstream Regulated 1 (NDRG1))

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This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].

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Featured NDRG1 Categories

NDRG1 Antibodies

High quality antibodies with extensive validation data.

NDRG1 ELISA Kits

Reliable ELISA kits for a wide range of species.

NDRG1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NDRG1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN184872
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN564518
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (1)
  • (3)
Cat. No. ABIN390922
Quantity 400 μL
Datasheet Datasheet

Recommended NDRG1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968777
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951436
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1152012
Quantity 96 tests
Datasheet Datasheet

Recommended NDRG1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312183
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2130785
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1097200
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our NDRG1 products

Ortega, Roefs, de Miguel Perez, Kooijmans, de Jong, Sluijter, Schiffelers, Vader: "Interfering with endolysosomal trafficking enhances release of bioactive exosomes." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 20, pp. 102014, (2019) (PubMed).

Chaudhari, Talwar, Lefebvre Dhellencourt, Ravanan: "CDDO and ATRA Instigate Differentiation of IMR32 Human Neuroblastoma Cells." in: Frontiers in molecular neuroscience, Vol. 10, pp. 310, (2017) (PubMed).

Ghalayini, Dong, Richardson, Assinder: "Proteolytic cleavage and truncation of NDRG1 in human prostate cancer cells, but not normal prostate epithelial cells." in: Bioscience reports, Vol. 33, Issue 3, (2014) (PubMed).

Lane, Saletta, Suryo Rahmanto, Kovacevic, Richardson: "N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion." in: PLoS ONE, Vol. 8, Issue 2, pp. e57273, (2013) (PubMed).

Mao, Sun, Feng, Ma, Zang, Dong, Zhang, Zheng: "The metastasis suppressor, N-myc downregulated gene 1 (NDRG1), is a prognostic biomarker for human colorectal cancer." in: PLoS ONE, Vol. 8, Issue 7, pp. e68206, (2013) (PubMed).

Jiang, Shen, Ye, Yang, Wang: "A novel molecular marker for early detection and evaluating prognosis of gastric cancer: N-myc downstream regulated gene-1 (NDRG1)." in: Scandinavian journal of gastroenterology, Vol. 45, Issue 7-8, pp. 898-908, (2010) (PubMed).

Drögemüller, Becker, Kessler, Kemter, Tetens, Jurina, Jäderlund, Flagstad, Perloski, Lindblad-Toh, Matiasek: "A deletion in the N-myc downstream regulated gene 1 (NDRG1) gene in Greyhounds with polyneuropathy." in: PLoS ONE, Vol. 5, Issue 6, pp. e11258, (2010) (PubMed).

Leth-Larsen, Lund, Hansen, Laenkholm, Tarin, Jensen, Ditzel: "Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 6, pp. 1436-49, (2009) (PubMed).

Schilling, Hjelmeland, Radiloff, Liu, Wakeman, Fielhauer, Foster, Lathia, Rich, Wang, Datto: "NDRG4 is required for cell cycle progression and survival in glioblastoma cells." in: The Journal of biological chemistry, Vol. 284, Issue 37, pp. 25160-9, (2009) (PubMed).

Coppinger, Repetti, Day, Dahlbeck, Mehlert, Staskawicz: "Overexpression of the plasma membrane-localized NDR1 protein results in enhanced bacterial disease resistance in Arabidopsis thaliana." in: The Plant journal : for cell and molecular biology, Vol. 40, Issue 2, pp. 225-37, (2004) (PubMed).

Synonyms and alternative names related to NDRG1

N-myc downstream regulated 1 (NDRG1), N-myc downstream regulated gene 1 (Ndrg1), N-myc downstream regulated 1 (Ndrg1), N-myc downstream regulated 1 S homeolog (ndrg1.S), N-myc downstream regulated 1 (ndrg1), N-myc downstream regulated 1a (ndrg1a), Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family (NDR1), N-myc downstream regulated 1 L homeolog (ndrg1.L), N-myc downstream regulated 1b (ndrg1b), CAP43, cap43, cb775, CMT4D, cmt4d, DRG-1, DRG1, drg1, GC4, gc4, HMSNL, hmsnl, NDR1, Ndr1, ndr1, ndrg1, NDRG1, ndrg1-a, ndrg1-b, ndrg1l, ndrg4, Ndrl, NMSL, nmsl, NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN, non race-specific disease resistance 1, PROXY1, proxy1, RIT42, rit42, RTP, rtp, TARG1, targ1, TDD5, tdd5, wu:fb60h02, xndrg1, xNDRG1-A, zgc:63944, zgc:73047

Protein level used designations for NDRG1

  • N-myc downstream-regulated gene 1 protein
  • differentiation-related gene 1 protein
  • nickel-specific induction protein Cap43
  • protein NDRG1
  • protein regulated by oxygen-1
  • reducing agents and tunicamycin-responsive protein
  • N-myc downstream regulated 1
  • protein Ndr1
  • N-myc downstream regulated gene 1
  • protein NDRG1-B
  • xNDRG1-B
  • protein NDRG1-like
  • protein NDRG1-A
  • xNDRG1-A
  • N-myc downstream regulated gene 1, like
  • N-myc downstream regulated gene 1b
  • n-myc downstream-regulated gene 1b
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