NDC80 Products
(NDC80 Kinetochore Complex Component Homolog (NDC80))
Categories
This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011].
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Featured NDC80 Categories
NDC80 Antibodies
High quality antibodies with extensive validation data.
NDC80 ELISA Kits
Reliable ELISA kits for a wide range of species.
NDC80 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NDC80 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6263548
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN564521
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN184821
Quantity
100 μg
Datasheet
Datasheet
Recommended NDC80 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648262
Quantity
96 tests
Datasheet
Datasheet
Recommended NDC80 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312158
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312160
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137068
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NDC80 products
: "PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells." in: Nature communications, Vol. 9, Issue 1, pp. 1106, (2018) (PubMed).: "Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics." in: The Journal of cell biology, Vol. 217, Issue 1, pp. 163-177, (2018) (PubMed).
: "Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability." in: eLife, Vol. 6, (2017) (PubMed).
: "Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells." in: Nature communications, Vol. 6, pp. 10036, (2015) (PubMed).
: "A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells." in: Oncogene, Vol. 33, Issue 33, pp. 4242-52, (2014) (PubMed).
: "The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit." in: Molecular biology of the cell, Vol. 25, Issue 5, pp. 594-605, (2014) (PubMed).
: "STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments." in: Journal of cell science, Vol. 127, Issue Pt 19, pp. 4225-33, (2014) (PubMed).
: "P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells." in: Cancers, Vol. 4, Issue 2, pp. 475-89, (2013) (PubMed).
: "The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells." in: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 9, pp. 1457-71, (2013) (PubMed).
: "Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation." in: Nature, Vol. 502, Issue 7469, pp. 110-3, (2013) (PubMed).
Synonyms and alternative names related to NDC80
NDC80, kinetochore complex component (NDC80), CG9938 gene product from transcript CG9938-RA (Ndc80), spindle pole body protein Ndc80 (ndc80), kinetochore protein Ndc80 (ndc80), NDC80 homolog, kinetochore complex component (S. cerevisiae) (ndc80), NDC80 kinetochore complex component (Ndc80), NDC80 kinetochore complex component (ndc80), NDC80 kinetochore complex component S homeolog (ndc80.S), 2610020P18Rik, AV139730, CG9938, Dmel\\CG9938, dmNdc80, dNdc80, HEC, Hec1, hec1, HEC1, HsHec1, hsNDC80, KNTC2, Kntc2, kntc2, kntc2l, ndc10, NDC80, tid3, TID3, wu:fb52e02, zgc:111801Protein level used designations for NDC80
- kinetochore associated 2
- CG9938-PA
- Hec1
- Ndc80-PA
- NDC80 homolog, kinetochore complex component (S. cerevisiae)
- NDC80 homolog, kinetochore complex component
- kinetochore protein NDC80 homolog
- kinetochore protein Ndc80
- Kinetochore protein NDC80 homolog
- highly expressed in cancer, rich in leucine heptad repeats
- kinetochore protein Hec1
- kinetochore-associated protein 2
- HEC (highly expressed in cancer)
- NDC80 kinetochore complex component homolog
- highly expressed in cancer protein
- retinoblastoma-associated protein HEC
- kinetochore spindle checkpoint protein Ndc80
- xNdc80
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