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NCOA6 Products

(Nuclear Receptor Coactivator 6 (NCOA6))

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The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011].

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Featured NCOA6 Categories

NCOA6 Antibodies

High quality antibodies with extensive validation data.

NCOA6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NCOA6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IF
Validations
  • (3)
Cat. No. ABIN564998
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7161865
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7161868
Quantity 100 μg
Datasheet Datasheet

Recommended NCOA6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6206228
Quantity 96 tests
Datasheet Datasheet

Recommended NCOA6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312136
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420318
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN6119399
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our NCOA6 products

Kopanja, Pandey, Huang, Rizwan Haroon Al Raheed, Guzman, Raychaudhuri: "p19Arf Inhibits Aggressive Progression of H-ras driven Hepatocellular Carcinoma." in: Carcinogenesis, (2018) (PubMed).

Chen, Fu, Dong, Wang, Shiah, Moore, Huang: "Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver." in: Hepatology (Baltimore, Md.), Vol. 56, Issue 4, pp. 1499-509, (2012) (PubMed).

Vicent, Nacht, Font-Mateu, Castellano, Gaveglia, Ballaré, Beato: "Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation." in: Genes & development, Vol. 25, Issue 8, pp. 845-62, (2011) (PubMed).

Lee, Kim, Goo, Lee, Lee, Lee: "Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 5, pp. 610-9, (2009) (PubMed).

Kim, Park, Yeom, Lee, Kim, Ko, Rhee, Kim, Lee, Kim, Oh, Lee, Lee, Kim: "Characterization of ASC-2 as an antiatherogenic transcriptional coactivator of liver X receptors in macrophages." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 7, pp. 966-74, (2009) (PubMed).

Garapaty, Xu, Trojer, Mahajan, Neubert, Samuels: "Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7542-52, (2009) (PubMed).

Surapureddi, Rana, Reddy, Goldstein: "Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha." in: Molecular pharmacology, Vol. 74, Issue 3, pp. 913-23, (2008) (PubMed).

Lee, Saha, Yang, Lee, Park, Suh, Lee, Chan, Roeder, Lee: "Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 49, pp. 19229-34, (2008) (PubMed).

Cho, Hong, Hong, Guo, Yu, Kim, Guszczynski, Dressler, Copeland, Kalkum, Ge: "PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex." in: The Journal of biological chemistry, Vol. 282, Issue 28, pp. 20395-406, (2007) (PubMed).

Synonyms and alternative names related to NCOA6

nuclear receptor coactivator 6 (NCOA6), nuclear receptor coactivator 6 (Tsp_14219), nuclear receptor coactivator 6 (Tsp_13372), nuclear receptor coactivator 6 (ncoa6), nuclear receptor coactivator 6 (LOC100196047), nuclear receptor coactivator 6 (Ncoa6), AIB3, Aib3, ASC-2, ASC2, gb:dq017635, mKIAA0181, ncoa6, Ncoa7, NRC, PRIP, RAP250, TRBP, Trbp, wu:fb25d11

Protein level used designations for NCOA6

  • nuclear receptor coactivator 6
  • Nuclear receptor coactivator 6
  • NRC RAP250
  • PPAR-interacting protein
  • activating signal cointegrator 2
  • activating signal cointegrator-2
  • amplified in breast cancer protein 3
  • amplified in breast cancer-3 protein
  • cancer-amplified transcriptional coactivator ASC-2
  • nuclear receptor coactivator RAP250
  • nuclear receptor-activating protein, 250 kDa
  • peroxisome proliferator-activated receptor interacting protein
  • peroxisome proliferator-activated receptor-interacting protein
  • thyroid hormone receptor binding protein
  • thyroid hormone receptor-binding protein
  • PPAR interacting protein PRIP
  • nuclear receptor-activating protein 250
  • peroxisome proliferator-activated receptor interacting protein,PRIP
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