NCOA3 Products
(Nuclear Receptor Coactivator 3 (NCOA3))
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The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010].
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Featured NCOA3 Categories
NCOA3 Antibodies
High quality antibodies with extensive validation data.
NCOA3 ELISA Kits
Reliable ELISA kits for a wide range of species.
NCOA3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NCOA3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (5)
Cat. No.
ABIN7441217
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7074886
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (3)
Cat. No.
ABIN3187987
Quantity
100 μL
Datasheet
Datasheet
Recommended NCOA3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958248
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958249
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5657459
Quantity
96 tests
Datasheet
Datasheet
Recommended NCOA3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312128
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407163
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407166
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NCOA3 products
: "Identification and validation of AIB1 and EIF5A2 for noninvasive detection of bladder cancer in urine samples." in: Oncotarget, Vol. 7, Issue 27, pp. 41703-41714, (2016) (PubMed).: "The High Expression of the microRNA 17-92 Cluster and its Paralogs, and the Downregulation of the Target Gene PTEN, Is Associated with Primary Cutaneous B-Cell Lymphoma Progression." in: The Journal of investigative dermatology, Vol. 135, Issue 6, pp. 1659-67, (2015) (PubMed).
: "Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 21, pp. 5983-91, (2012) (PubMed).
: "Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation." in: Cancer research, Vol. 70, Issue 16, pp. 6477-85, (2010) (PubMed).
: "Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption." in: Alcohol and alcoholism (Oxford, Oxfordshire), Vol. 45, Issue 4, pp. 303-11, (2010) (PubMed).
: "Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 6, pp. 1187-202, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Global characterization of transcriptional impact of the SRC-3 coregulator." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 4, pp. 859-72, (2010) (PubMed).
: "Androgen modulation of coregulator expression in prostate cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 4, pp. 572-83, (2009) (PubMed).
: "Estrogen receptor co-activator (AIB1) protein expression by automated quantitative analysis (AQUA) in a breast cancer tissue microarray and association with patient outcome." in: Breast cancer research and treatment, Vol. 115, Issue 1, pp. 77-85, (2009) (PubMed).
Synonyms and alternative names related to NCOA3
nuclear receptor coactivator 3 (NCOA3), nuclear receptor coactivator 3 (Ncoa3), nuclear receptor coactivator 3 S homeolog (ncoa3.S), 2010305B15Rik, ACTR, Actr, actr, AIB-1, aib-1, AIB1, Aib1, aib1, AW321064, bHLHe42, CAGH16, cagh16, CTG26, ctg26, KAT13B, kat13b, NCOA3, p/Cip, pCIP, pCip, pcip, RAC3, Rac3, rac3, SRC-3, src-3, SRC3, Src3, src3, TNRC14, tnrc14, TNRC16, tnrc16, TRAM-1, Tram-1, tram-1, Tram1, xSRC-3Protein level used designations for NCOA3
- nuclear receptor coactivator 3
- CBP-interacting protein
- amplified in breast cancer 1 protein
- class E basic helix-loop-helix protein 42
- receptor-associated coactivator 3
- steroid receptor coactivator protein 3
- thyroid hormone receptor activator molecule 1
- steroid receptor coactivator 3
- AIB-1
- NCoA-3
- RAC-3
- SRC-3
- amplified in breast cancer-1 protein homolog
- retinoid X receptor-interacting coactivator xSRC-3
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