NCOA1 Products
(Nuclear Receptor Coactivator 1 (NCOA1))
Categories
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured NCOA1 Categories
NCOA1 Antibodies
High quality antibodies with extensive validation data.
NCOA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NCOA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NCOA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN3021492
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN391825
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN7269005
Quantity
100 μL
Datasheet
Datasheet
Recommended NCOA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969007
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969006
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Validations
Cat. No.
ABIN1145493
Quantity
96 tests
Datasheet
Datasheet
Recommended NCOA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312124
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422733
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (1)
Cat. No.
ABIN2732662
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our NCOA1 products
: "Chemotherapy-Induced Ca(2+) Release Stimulates Breast Cancer Stem Cell Enrichment." in: Cell reports, Vol. 18, Issue 8, pp. 1946-1957, (2017) (PubMed).: "Isoform-selective activation of human constitutive androstane receptor by Ginkgo biloba extract: functional analysis of the SV23, SV24, and SV25 splice variants." in: The Journal of pharmacology and experimental therapeutics, Vol. 339, Issue 2, pp. 704-15, (2011) (PubMed).
: "Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor." in: The Journal of pharmacology and experimental therapeutics, Vol. 336, Issue 3, pp. 816-26, (2011) (PubMed).
: "Human pregnane X receptor agonism by Ginkgo biloba extract: assessment of the role of individual ginkgolides." in: The Journal of pharmacology and experimental therapeutics, Vol. 335, Issue 3, pp. 771-80, (2010) (PubMed).
: "Androgen modulation of coregulator expression in prostate cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 4, pp. 572-83, (2009) (PubMed).
: "The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors." in: The Journal of biological chemistry, Vol. 284, Issue 29, pp. 19554-63, (2009) (PubMed).
: "Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate." in: Endocrinology, Vol. 151, Issue 1, pp. 394-405, (2009) (PubMed).
: "Functional characterization of the native NH2-terminal transactivation domain of the human androgen receptor: binding kinetics for interactions with TFIIF and SRC-1a." in: Biochemistry, Vol. 47, Issue 11, pp. 3352-9, (2008) (PubMed).
: "In vitro fluorescence anisotropy analysis of the interaction of full-length SRC1a with estrogen receptors alpha and beta supports an active displacement model for coregulator utilization." in: The Journal of biological chemistry, Vol. 282, Issue 5, pp. 2765-75, (2007) (PubMed).
: "The pure estrogen receptor antagonist ICI 182,780 promotes a novel interaction of estrogen receptor-alpha with the 3',5'-cyclic adenosine monophosphate response element-binding protein-binding ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2695-710, (2006) (PubMed).
Synonyms and alternative names related to NCOA1
nuclear receptor coactivator 1 (NCOA1), nuclear receptor coactivator 1 (ncoa1), nuclear receptor coactivator 1 (Ncoa1), bHLHe42, bHLHe74, F-SRC-1, KAT13A, NCOA1, RIP160, si:dkey-5g7.6, si:dkey-34f16.6, SRC-1, SRC1Protein level used designations for NCOA1
- Hin-2 protein
- PAX3/NCOA1 fusion protein
- class E basic helix-loop-helix protein 74
- renal carcinoma antigen NY-REN-52
- steroid receptor coactivator-1
- nuclear receptor coactivator 1
- steroid receptor coactivator 1
- DKEY-34F16.7
- SRC1
- NCoA-1
- SRC-a/NCoA-1
- mNRC-1
- nuclear receptor coactivator protein 1
- SRC-1
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