NCK1 Products
(NCK Adaptor Protein 1 (NCK1))
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The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010].
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Featured NCK1 Categories
NCK1 Antibodies
High quality antibodies with extensive validation data.
NCK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NCK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN969545
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN561929
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, FACS, IHC (p), EIA
Validations
- (5)
Cat. No.
ABIN1108388
Quantity
0.1 mg
Datasheet
Datasheet
Recommended NCK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883862
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6384453
Quantity
96 tests
Datasheet
Datasheet
Recommended NCK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124117
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312105
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312103
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our NCK1 products
: "SDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells." in: European journal of immunology, Vol. 45, Issue 2, pp. 551-61, (2015) (PubMed).: "The adapter proteins ADAP and Nck cooperate in T cell adhesion." in: Molecular immunology, Vol. 60, Issue 1, pp. 72-9, (2014) (PubMed).
: "Nck recruitment to the TCR required for ZAP70 activation during thymic development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 3, pp. 1103-12, (2013) (PubMed).
: "The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway." in: Cellular signalling, Vol. 22, Issue 5, pp. 848-56, (2010) (PubMed).
: "Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization." in: Molecular and cellular biology, Vol. 28, Issue 6, pp. 2035-46, (2008) (PubMed).
: "The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains." in: The Journal of biological chemistry, Vol. 281, Issue 26, pp. 18236-45, (2006) (PubMed).
: "Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress." in: The Journal of biological chemistry, Vol. 281, Issue 36, pp. 26633-44, (2006) (PubMed).
: "The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network." in: Molecular and cellular biology, Vol. 23, Issue 13, pp. 4586-97, (2003) (PubMed).
: "EphB receptors interact with NMDA receptors and regulate excitatory synapse formation." in: Cell, Vol. 103, Issue 6, pp. 945-56, (2001) (PubMed).
: "Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor." in: Oncogene, Vol. 20, Issue 30, pp. 4058-69, (2001) (PubMed).
Synonyms and alternative names related to NCK1
NCK adaptor protein 1 (NCK1), NCK adaptor protein 1 (Nck1), non-catalytic region of tyrosine kinase adaptor protein 1 (Nck1), NCK adaptor protein 1b (nck1b), NCK adaptor protein 1 L homeolog (nck1.L), 6330586M15Rik, D230010O13Rik, NCK, Nck, nck, nck-1, Nck-1, NCK1, Nck1, nck1-a, nck1-b, NCKalpha, nckalphaProtein level used designations for NCK1
- NCK tyrosine kinase
- SH2/SH3 adaptor protein NCK-alpha
- cytoplasmic protein NCK1
- melanoma NCK protein
- non-catalytic region of tyrosine kinase
- non-catalytic region of tyrosine kinase adaptor protein 1
- NCK adaptor protein 1
- cytoplasmic protein NCK1-like
- nck1
- NCK adaptor protein 1 L homeolog
- SH2/SH3 adaptor protein
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