NCF2 Products
(Neutrophil Cytosolic Factor 2 (NCF2))
Categories
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010].
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Featured NCF2 Categories
NCF2 Antibodies
High quality antibodies with extensive validation data.
NCF2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NCF2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NCF2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (4)
Cat. No.
ABIN7161498
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN6263535
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN3021641
Quantity
100 μL
Datasheet
Datasheet
Recommended NCF2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958175
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951326
Quantity
96 tests
Datasheet
Datasheet
Recommended NCF2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312095
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312097
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7415524
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NCF2 products
: "Testosterone improves erectile function through inhibition of reactive oxygen species generation in castrated rats." in: PeerJ, Vol. 4, pp. e2000, (2016) (PubMed).: "Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value." in: British journal of cancer, Vol. 104, Issue 1, pp. 110-9, (2011) (PubMed).
: "Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating" in: The Journal of biological chemistry, Vol. 274, Issue 47, pp. 33644-53, (1999) (PubMed).
: "Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways." in: The Journal of biological chemistry, Vol. 272, Issue 27, pp. 17204-8, (1997) (PubMed).
: "NADPH oxidase activity is independent of p47phox in vitro." in: The Journal of biological chemistry, Vol. 271, Issue 37, pp. 22578-82, (1996) (PubMed).
: "Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 22, pp. 10650-4, (1994) (PubMed).
: "Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src." in: Science (New York, N.Y.), Vol. 248, Issue 4956, pp. 727-30, (1990) (PubMed).
Synonyms and alternative names related to NCF2
neutrophil cytosolic factor 2 (NCF2), neutrophil cytosolic factor 2 L homeolog (ncf2.L), neutrophil cytosolic factor 2 (ncf2), neutrophil cytosolic factor 2 (p67phox), neutrophil cytosol factor 2 (VDBG_06643), hypothetical protein (PGTG_05816), neutrophil cytosolic factor 2 (LOC100136240), neutrophil cytosolic factor 2 (Ncf2), MGC81877, NCF-2, Ncf-2, noxa2, NOXA2, p67-phox, P67-PHOX, p67phox, P67PHOX, zgc:158405Protein level used designations for NCF2
- neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)
- neutrophil cytosolic factor 2
- neutrophil cytosol factor 2
- predicted neutrophil cytosolic factor 2
- p67phox
- p67-phox
- NADPH oxidase cytosolic protein p67phox
- NADPH oxidase cytosolic protein
- 67 kDa neutrophil oxidase factor
- NADPH oxidase activator 2
- chronic granulomatous disease, autosomal 2
- neutrophil NADPH oxidase factor 2
- neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
- NADPH oxidase subunit (67 kD)
- NADPH oxidase subunit (67kDa)
- NCF-2
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