N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Products
(N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
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This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Categories
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Antibodies
High quality antibodies with extensive validation data.
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7434806
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN513533
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7142987
Quantity
100 μL
Datasheet
Datasheet
Recommended N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958012
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5657146
Quantity
96 tests
Datasheet
Datasheet
Recommended N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1345778
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124089
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345780
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 products
: "A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase." in: ACS chemical biology, Vol. 14, Issue 1, pp. 11-19, (2019) (PubMed).: "The investigation of ceranib-2 on apoptosis and drug interaction with carboplatin in human non small cell lung cancer cells in vitro." in: Cytotechnology, Vol. 70, Issue 1, pp. 387-396, (2018) (PubMed).
: "Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION." in: The Journal of biological chemistry, Vol. 291, Issue 5, pp. 2422-34, (2016) (PubMed).
: "Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).
: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." in: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).
: "Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells." in: Biochimica et biophysica acta, Vol. 1841, Issue 4, pp. 552-62, (2014) (PubMed).
: "Ceramide biosynthesis and metabolism in trophoblast syncytialization." in: Molecular and cellular endocrinology, Vol. 362, Issue 1-2, pp. 48-59, (2012) (PubMed).
: "Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 228-43, (2012) (PubMed).
: "Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor." in: Molecular and cellular biology, Vol. 32, Issue 21, pp. 4419-31, (2012) (PubMed).
: "Clinical utility of serum autoantibodies detected by protein microarray in melanoma." in: International journal of proteomics, Vol. 2011, pp. 413742, (2011) (PubMed).
Synonyms and alternative names related to N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1
N-acylsphingosine amidohydrolase 1 (ASAH1), N-acylsphingosine amidohydrolase 1 (Asah1), N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1), N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog (asah1.L), N-acylsphingosine amidohydrolase (acid ceramidase) 1a (asah1a), Acid ceramidase (asah-1), N-acylsphingosine amidohydrolase (acid ceramidase) 1b (asah1b), 2310081N20Rik, AC, ACDase, ASAH, Asah, asah1, ASAH1, MGC82286, PHP, PHP32, SMAPME, zgc:66026, zgc:101637Protein level used designations for N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1
- acid CDase
- acid ceramidase
- acylsphingosine deacylase
- putative 32 kDa heart protein
- ACDase
- Acylsphingosine deacylase
- N-acylsphingosine amidohydrolase 1
- AC
- N-acylsphingosine amidohydrolase (acid ceramidase) 1
- N-acylsphingosine amidohydrolase
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