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NADPH Oxidase 4 Products

(NADPH Oxidase 4 (NOX4))
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009].

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Featured NADPH Oxidase 4 Categories

NADPH Oxidase 4 Antibodies

High quality antibodies with extensive validation data.

NADPH Oxidase 4 ELISA Kits

Reliable ELISA kits for a wide range of species.

NADPH Oxidase 4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NADPH Oxidase 4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN5542344
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN6144752
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7434350
Quantity 100 μL
Datasheet Datasheet

Recommended NADPH Oxidase 4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6958026
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958027
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6958028
Quantity 96 tests
Datasheet Datasheet

Recommended NADPH Oxidase 4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312830
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505064
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN2752696
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our NADPH Oxidase 4 products

Chakraborti, Pramanick, Saha, Sarkar, Singh, Stewart, Maity: "Biphasic changes in TGF-β1 signaling drive NSAID-induced multi-organ damage." in: Free radical biology & medicine, Vol. 160, pp. 125-140, (2020) (PubMed).

Bitar, Nader, Al-Ali, Al Madhoun, Arefanian, Al-Mulla: "Hydrogen Sulfide Donor NaHS Improves Metabolism and Reduces Muscle Atrophy in Type 2 Diabetes: Implication for Understanding Sarcopenic Pathophysiology." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 6825452, (2019) (PubMed).

Lanza-Jacoby, Cheng: "3,3'-Diindolylmethane enhances apoptosis in docetaxel-treated breast cancer cells by generation of reactive oxygen species." in: Pharmaceutical biology, Vol. 56, Issue 1, pp. 407-414, (2019) (PubMed).

Goitre, DiStefano, Moglia, Nobiletti, Baldini, Trabalzini, Keubel, Trapani, Shuvaev, Muzykantov, Sarelius, Retta, Glading: "Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium." in: Scientific reports, Vol. 7, Issue 1, pp. 8296, (2019) (PubMed).

Buck, Hack, Berg, Berg, Kunz, Mayerhofer: "The NADPH oxidase 4 is a major source of hydrogen peroxide in human granulosa-lutein and granulosa tumor cells." in: Scientific reports, Vol. 9, Issue 1, pp. 3585, (2019) (PubMed).

García-Arroyo, Gonzaga, Muñoz-Jiménez, Osorio-Alonso, Iroz, Vecchio, Tapia, Roncal-Jiménez, Johnson, Sánchez-Lozada: "Antioxidant supplements as a novel mean for blocking recurrent heat stress-induced kidney damage following rehydration with fructose-containing beverages." in: Free radical biology & medicine, Vol. 141, pp. 182-191, (2019) (PubMed).

Chen, Tao, Li, Zeng, Zhang, Yao: "Anagliptin protects neuronal cells against endogenous amyloid β (Aβ)-induced cytotoxicity and apoptosis." in: Artificial cells, nanomedicine, and biotechnology, Vol. 47, Issue 1, pp. 2213-2220, (2019) (PubMed).

Ikeda, Matsushima, Okabe, Ikeda, Ishikita, Tadokoro, Enzan, Yamamoto, Sada, Deguchi, Morimoto, Ide, Tsutsui: "Blockade of L-type Ca2+ channel attenuates doxorubicin-induced cardiomyopathy via suppression of CaMKII-NF-κB pathway." in: Scientific reports, Vol. 9, Issue 1, pp. 9850, (2019) (PubMed).

Wegner, Campos, Robbins, Haddad, Cunningham, Yik, Christiansen, Haudenschild: "Acute Changes in NADPH Oxidase 4 in Early Post-Traumatic Osteoarthritis." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, (2019) (PubMed).

Li, Li, Rao, Liu, Zhang, Liu, Wang, Wang, Liu, Liu: "Curcumin ameliorates atrophy of seminal vesicle via reduction of oxidative stress in castrated mice." in: PeerJ, Vol. 7, pp. e7192, (2019) (PubMed).

Synonyms and alternative names related to NADPH Oxidase 4

NADPH oxidase 4 (NOX4), NADPH oxidase 4 (Nox4), NADPH oxidase 4 (nox4), NADPH oxidase 4 (PTRG_09562), AI648021, KOX, KOX-1, nox4, NOX4, RENOX

Protein level used designations for NADPH Oxidase 4

  • kidney oxidase-1
  • kidney superoxide-producing NADPH oxidase
  • renal NAD(P)H-oxidase
  • KOX-1
  • superoxide-generating NADPH oxidase 4
  • kox-1
  • NADPH oxidase 4
  • predicted NADPH oxidase-4
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