NAD-ME Products
(NAD Dependent Malate Dehydrogenase (NAD-ME))
Categories
This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009].
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Featured NAD-ME Categories
NAD-ME Antibodies
High quality antibodies with extensive validation data.
NAD-ME ELISA Kits
Reliable ELISA kits for a wide range of species.
NAD-ME Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NAD-ME Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
IHC, IF
Validations
- (5)
Cat. No.
ABIN7074757
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (4)
Cat. No.
ABIN2784265
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6263183
Quantity
100 μL
Datasheet
Datasheet
Recommended NAD-ME ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958018
Quantity
96 tests
Datasheet
Datasheet
Recommended NAD-ME Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124100
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2726776
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2830403
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NAD-ME products
: "Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells." in: Archives of biochemistry and biophysics, Vol. 488, Issue 2, pp. 100-4, (2009) (PubMed).: "Succinate is the controller of O2-/H2O2 release at mitochondrial complex I : negative modulation by malate, positive by cyanide." in: Journal of bioenergetics and biomembranes, Vol. 41, Issue 4, pp. 387-93, (2009) (PubMed).
: "Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line." in: The Journal of biological chemistry, Vol. 284, Issue 51, pp. 35359-67, (2009) (PubMed).
: "Mycobacterium avium-Mycobacterium intracellular complex-induced suppression of T-cell proliferation in vitro by regulation of monocyte accessory cell activity." in: Infection and immunity, Vol. 58, Issue 5, pp. 1369-78, (1990) (PubMed).
Synonyms and alternative names related to NAD-ME
malic enzyme 2 (ME2), malic enzyme 2, NAD(+)-dependent, mitochondrial (Me2), malic enzyme 2 (Me2), malic enzyme 2, NAD(+)-dependent, mitochondrial S homeolog (me2.S), malic enzyme 2, NAD(+)-dependent, mitochondrial (me2), AW120568, D030040L20Rik, NAD-ME, ODS1, zgc:100941Protein level used designations for NAD-ME
- NAD-ME
- NAD-dependent malic enzyme, mitochondrial
- malate dehydrogenase
- pyruvic-malic carboxylase
- malic enzyme 2
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