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NACA Products

(Nascent Polypeptide Associated Complex alpha 1 (NACa1))
The protein encoded by this gene associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). NAC binds to nascent proteins as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. However, nascent proteins with an exposed signal peptide will not be bound by the encoded protein, enabling them to bind the SRP and enter the secretory pathway. This protein has been determined to be an IgE autoantigen in atopic dermatitis patients. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Featured NACA Categories

NACA Antibodies

High quality antibodies with extensive validation data.

NACA ELISA Kits

Reliable ELISA kits for a wide range of species.

NACA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NACA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN518179
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN337196
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6263507
Quantity 100 μL
Datasheet Datasheet

Recommended NACA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968799
Quantity 96 tests
Datasheet Datasheet

Recommended NACA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124113
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311914
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3084268
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NACA products

Puigmulé, López-Hellin, Suñé, Tornavaca, Camaño, Tejedor, Meseguer: "Differential proteomic analysis of cyclosporine A-induced toxicity in renal proximal tubule cells." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 24, Issue 9, pp. 2672-86, (2009) (PubMed).

Synonyms and alternative names related to NACA

nascent polypeptide-associated complex alpha polypeptide (Naca), nascent polypeptide-associated complex alpha subunit (naca), nascent polypeptide-associated complex alpha subunit (NACA), nascent polypeptide-associated complex alpha subunit (Naca), AL022831, AL024382, Gm1878, ik:tdsubc_2b5, mKIAA0363, NACA1, nkn, skNAC, tdsubc_2b5, xx:tdsubc_2b5

Protein level used designations for NACA

  • alpha-NAC, muscle-specific form
  • alpha-NAC/1.9.2
  • nascent polypeptide-associated complex alpha subunit
  • nascent polypeptide-associated complex subunit alpha
  • nascent polypeptide-associated complex subunit alpha, muscle-specific form
  • NAC-alpha
  • alpha-NAC
  • no knack
  • sknac
  • nascent-polypeptide-associated complex alpha polypeptide
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