NAC1 Products
(Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
Categories
This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012].
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Featured NAC1 Categories
NAC1 Antibodies
High quality antibodies with extensive validation data.
NAC1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NAC1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN202717
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
Cat. No.
ABIN6243841
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN969307
Quantity
100 μL
Datasheet
Datasheet
Recommended NAC1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3084172
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3124212
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NAC1 products
: "Nucleus accumbens-associated protein-1 promotes glycolysis and survival of hypoxic tumor cells via the HDAC4-HIF-1α axis." in: Oncogene, (2017) (PubMed).: "Nucleus accumbens-1/GADD45GIP1 axis mediates cisplatin resistance through cellular senescence in ovarian cancer." in: Oncology letters, Vol. 13, Issue 6, pp. 4713-4719, (2017) (PubMed).
: "Loss of NAC1 expression is associated with defective bony patterning in the murine vertebral axis." in: PLoS ONE, Vol. 8, Issue 7, pp. e69099, (2013) (PubMed).
: "NAC1, A POZ/BTB protein interacts with Parkin and may contribute to Parkinson's disease." in: Neuroscience, Vol. 257, pp. 86-95, (2013) (PubMed).
: "Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas." in: British journal of cancer, Vol. 107, Issue 2, pp. 300-7, (2012) (PubMed).
: "NAC1, a BTB/POZ protein overexpressed in uterine sarcomas." in: Anticancer research, Vol. 32, Issue 9, pp. 3841-5, (2012) (PubMed).
: "Nucleus Accumbens 1, a Pox virus and Zinc finger/Bric-a-brac Tramtrack Broad protein binds to TAR DNA-binding protein 43 and has a potential role in Amyotrophic Lateral Sclerosis." in: Neuroscience, Vol. 227, pp. 44-54, (2012) (PubMed).
: "Amplification of the ch19p13.2 NACC1 locus in ovarian high-grade serous carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 24, Issue 5, pp. 638-45, (2011) (PubMed).
: "Cell cycle-dependent alteration in NAC1 nuclear body dynamics and morphology." in: Physical biology, Vol. 8, Issue 1, pp. 15005, (2011) (PubMed).
: "Novel events in the molecular regulation of muscle mass in critically ill patients." in: The Journal of physiology, Vol. 589, Issue Pt 15, pp. 3883-95, (2011) (PubMed).
Synonyms and alternative names related to NAC1
nucleus accumbens associated 1 (NACC1), nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (Nacc1), nucleus accumbens associated 1 (Nacc1), 2010001H03Rik, 4930511N13Rik, BEND8, BTBD14B, Btbd14b, BTBD30, NAC-1, Nac-1, NAC1, Nac1, NACC1Protein level used designations for NAC1
- BEN domain containing 8
- BTB/POZ domain-containing protein 14B
- nucleus accumbens-associated protein 1
- transcriptional repressor NAC1
- nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
- BTB (POZ) domain containing 14B
- NAC-1
- nucleus accumbens-1
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