MYO9B Products
(Myosin IXB (MYO9B))
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This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin\; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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Featured MYO9B Categories
MYO9B Antibodies
High quality antibodies with extensive validation data.
Recommended MYO9B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6257337
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7184482
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN185642
Quantity
100 μg
Datasheet
Datasheet
Recommended MYO9B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311840
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MYO9B products
: "The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity." in: PLoS ONE, Vol. 9, Issue 1, pp. e87402, (2014) (PubMed).: "Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect." in: Nature genetics, Vol. 37, Issue 12, pp. 1341-4, (2005) (PubMed).
Synonyms and alternative names related to MYO9B
myosin IXB (MYO9B), myosin IXb (Myo9b), myosin IXb (myo9b), unconventional myosin-IXb (LOC100450445), myosin IXB (Myo9b), CELIAC4, fb53f01, MYO9B, MYR5, si:dkeyp-66d1.8, wu:fb53f01, wu:fc47c07Protein level used designations for MYO9B
- myosin-IXb
- unconventional myosin IXb
- unconventional myosin-9b
- unconventional myosin-IXb
- Unconventional myosin from rat 3
- myr 5
- myosin IXB
- myosin-IXb-like
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