MYH11 Products
(Myosin Heavy Chain 11, Smooth Muscle (MYH11))
Categories
The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured MYH11 Categories
MYH11 Antibodies
High quality antibodies with extensive validation data.
MYH11 ELISA Kits
Reliable ELISA kits for a wide range of species.
MYH11 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MYH11 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, WB, IP, ICC
Validations
- (4)
Cat. No.
ABIN7441043
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
IHC, WB, IP, ICC
Validations
- (4)
Cat. No.
ABIN7445579
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
IHC, IF, FACS, StM
Validations
- (4)
Cat. No.
ABIN6940156
Quantity
100 μg
Datasheet
Datasheet
Recommended MYH11 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968748
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957965
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1143669
Quantity
96 tests
Datasheet
Datasheet
Recommended MYH11 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420975
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407850
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7404671
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MYH11 products
: "An injectable liposome for sustained release of tanshinone IIA to the treatment of acute blunt muscle injury by augmenting autophagy and alleviating oxidative stress." in: American journal of translational research, Vol. 12, Issue 8, pp. 4189-4203, (2020) (PubMed).: "Heterogeneous Cellular Contributions to Elastic Laminae Formation in Arterial Wall Development." in: Circulation research, Vol. 125, Issue 11, pp. 1006-1018, (2019) (PubMed).
: "Perivascular adipose tissue-derived leptin promotes vascular smooth muscle cell phenotypic switching via p38 mitogen-activated protein kinase in metabolic syndrome rats." in: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 8, pp. 954-965, (2014) (PubMed).
: "Enhanced expression of MYF5 and MYOD1 in fibroblast cells via the forced expression of bos taurus MYF5." in: Cell biology international, Vol. 37, Issue 9, pp. 972-6, (2013) (PubMed).
: "Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway." in: The Journal of biological chemistry, Vol. 281, Issue 39, pp. 28555-64, (2006) (PubMed).
: "Mapping of familial thoracic aortic aneurysm/dissection with patent ductus arteriosus to 16p12.2-p13.13." in: Circulation, Vol. 112, Issue 2, pp. 200-6, (2005) (PubMed).
Synonyms and alternative names related to MYH11
myosin, heavy polypeptide 11, smooth muscle (Myh11), myosin heavy chain 11 (Myh11), myosin heavy chain 11 (MYH11), myosin, heavy chain 11, smooth muscle (MYH11), myosin, heavy chain 11a, smooth muscle (myh11a), AAT4, AV071570, FAA4, myh11, myosin, SM1, SM2, SMHC, smMHC, SMMHCProtein level used designations for MYH11
- myosin heavy chain 11, smooth muscle
- myosin heavy chain, smooth muscle isoform
- myosin-11
- SMMHC
- myosin heavy chain 11
- myosin heavy chain 21
- myosin, heavy polypeptide 11, smooth muscle
- smooth muscle myosin heavy chain
- MHC
- gizzard smooth muscle
- heavy polypeptide 11
- myosin heavy chain, gizzard smooth muscle
- smooth muscle
- myosin heavy chain SMA
- meltdown
- mlt
- myosin, heavy polypeptide 11, smooth muscle a
- smmhc
- LOW QUALITY PROTEIN: myosin-11
- myosin, heavy chain 11, smooth muscle
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