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Myeloid Differentiation Primary Response Gene (88) Products

(Myeloid Differentiation Primary Response Gene (88) (MYD88))

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This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].

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Myeloid Differentiation Primary Response Gene (88) Antibodies

High quality antibodies with extensive validation data.

Myeloid Differentiation Primary Response Gene (88) ELISA Kits

Reliable ELISA kits for a wide range of species.

Myeloid Differentiation Primary Response Gene (88) Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Myeloid Differentiation Primary Response Gene (88) Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7433990
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Human, Mouse, Rat
Application WB, ELISA, IP, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (6)
  • (5)
Cat. No. ABIN736881
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF, FACS
Validations
  • (16)
Cat. No. ABIN185362
Quantity 100 μg
Datasheet Datasheet

Recommended Myeloid Differentiation Primary Response Gene (88) ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957941
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968723
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968724
Quantity 96 tests
Datasheet Datasheet

Recommended Myeloid Differentiation Primary Response Gene (88) Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311733
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2130705
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311732
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our Myeloid Differentiation Primary Response Gene (88) products

Pham, Ban, Lee, Hong, Lee, Truong, Lillehoj, Hong: "MicroRNA gga-miR-10a-mediated transcriptional regulation of the immune genes in necrotic enteritis afflicted chickens." in: Developmental and comparative immunology, Vol. 102, pp. 103472, (2020) (PubMed).

Matheson, Eid, Wilson, Graham, Matheson, Weaver, Downard, Smith: "Damage-associated molecular patterns in resuscitated hemorrhagic shock are mitigated by peritoneal fluid administration." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 315, Issue 3, pp. L339-L347, (2019) (PubMed).

Dowling, Tate, Rosli, Bourke, Bitto, Lauterbach, Cheung, Ve, Kobe, Golenbock, Mansell: "The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 202, Issue 8, pp. 2384-2396, (2019) (PubMed).

Russell, Creskey, Muralidharan, Li, Gao, Chen, Larocque, Lavoie, Farnsworth, Rosu-Myles, Hashem, Yauk, Cao, Van Domselaar, Cyr, Li: "Unveiling Integrated Functional Pathways Leading to Enhanced Respiratory Disease Associated With Inactivated Respiratory Syncytial Viral Vaccine." in: Frontiers in immunology, Vol. 10, pp. 597, (2019) (PubMed).

Ji, Xiao, Liu, Tang: "Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway." in: Stem cells international, Vol. 2019, pp. 9274585, (2019) (PubMed).

Zhang, Fei, Tao, Li, Shen, Wang, Liu, Xu: "Neuroprotective Effect of Modified Xijiao Dihuang Decoction against Oxygen-Glucose Deprivation and Reoxygenation-Induced Injury in PC12 Cells: Involvement of TLR4-MyD88/NF-κB Signaling Pathway." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 3848595, (2018) (PubMed).

Javmen, Szmacinski, Lakowicz, Toshchakov: "Blocking TIR Domain Interactions in TLR9 Signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 3, pp. 995-1006, (2018) (PubMed).

De Nardo, Balka, Cardona Gloria, Rao, Latz, Masters: "Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling." in: The Journal of biological chemistry, Vol. 293, Issue 39, pp. 15195-15207, (2018) (PubMed).

Li, Zhou, Wei, Chen, Geng, Zheng, Chai, Li, Jiang: "miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor." in: Scientific reports, Vol. 6, pp. 27914, (2018) (PubMed).

Wang, Yuan, Wang, Yang, Chen, Liu, Song, Feng, Tan, Jia: "Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway." in: Integrative cancer therapies, Vol. 16, Issue 4, pp. 505-515, (2018) (PubMed).

Synonyms and alternative names related to Myeloid Differentiation Primary Response Gene (88)

myeloid differentiation primary response 88 (MYD88), myeloid differentiation primary response 88 S homeolog (myd88.S), myeloid differentiation primary response gene 88 (Myd88), CG2078 gene product from transcript CG2078-RB (Myd88), myeloid differentiation primary response 88 (Myd88), myeloid differentiation primary response 88 (myd88), myeloid differentiation primary response protein MyD88-A (LOC413194), myeloid differentiation primary response protein MyD88 (LOC100118553), myeloid differentiation factor 88 (LOC575153), myeloid differentiation primary response 88 L homeolog (myd88.L), CG2078, Dmel\\CG2078, DMMYD88, DmMyD88, DmMyd88, dMyD88, dMyd88, EP(2)2535, GB12344, Kra, kra, LD20892, MGC84928, MYD88, MyD88, myd88, myd88-a, myd88-b, MYD88D, myd88d, Myd88F, NV10640, XMyD88, zgc:103541

Protein level used designations for Myeloid Differentiation Primary Response Gene (88)

  • myeloid differentiation primary response gene (88)
  • myeloid differentiation primary response protein MyD88
  • myeloid differentiation primary response protein MyD88-B
  • Toll/IL-1 receptor binding protein MyD88-B
  • CG2078-PA
  • CG2078-PB
  • Myd88-PA
  • Myd88-PB
  • Myd88F
  • krapfen
  • myeloid differentiation primary response gene 88
  • myeloid differentiation primary response factor 88
  • zMyD88
  • myeloid differentiation factor 88
  • myeloid differentiation primary response protein 88
  • myeloid differentiation response protein 88
  • Toll/IL-1 receptor binding protein MyD88
  • Toll/IL-1 receptor binding protein MyD88-A
  • myeloid differentiation primary response protein MyD88-A
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