MXD3 Products
(MAX Dimerization Protein 3 (MXD3))
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This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008].
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Featured MXD3 Categories
MXD3 Antibodies
High quality antibodies with extensive validation data.
MXD3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MXD3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN949698
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7159074
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (2)
Cat. No.
ABIN184841
Quantity
100 μg
Datasheet
Datasheet
Recommended MXD3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN1098770
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311688
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2130697
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MXD3 products
: "Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells." in: Blood cells, molecules & diseases, Vol. 54, Issue 4, pp. 329-35, (2015) (PubMed).: "MXD3 regulation of DAOY cell proliferation dictated by time course of activation." in: BMC cell biology, Vol. 15, pp. 30, (2014) (PubMed).
: "Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia." in: British journal of haematology, Vol. 167, Issue 4, pp. 487-99, (2014) (PubMed).
: "Histone deacetylase activity is necessary for left-right patterning during vertebrate development." in: BMC developmental biology, Vol. 11, pp. 29, (2011) (PubMed).
: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).
: "Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation." in: The EMBO journal, Vol. 14, Issue 22, pp. 5646-59, (1996) (PubMed).
Synonyms and alternative names related to MXD3
MAX dimerization protein 3 (mxd3), MAX dimerization protein 3 (MXD3), Max dimerization protein 3 (Mxd3), MAX dimerization protein 3 L homeolog (mxd3.L), 4631412E13Rik, BHLHC13, bHLHc13, Mad, Mad3, MAD3, MYX, Myx, zgc:66281Protein level used designations for MXD3
- MAX dimerization protein 3
- Max-associated protein 3
- Max-interacting transcriptional repressor MAD3
- class C basic helix-loop-helix protein 13
- max dimerization protein 3
- max dimerizer 3
- max-associated protein 3
- Mad3
- max-interacting transcriptional repressor MAD3
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