MXD1 Products
(MAX Dimerization Protein 1 (MXD1))
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This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011].
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Featured MXD1 Categories
MXD1 Antibodies
High quality antibodies with extensive validation data.
MXD1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MXD1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MXD1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1539192
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
- (1)
Cat. No.
ABIN599397
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Mouse, Rabbit
Application
WB
Validations
- (1)
Cat. No.
ABIN6746140
Quantity
100 μL
Datasheet
Datasheet
Recommended MXD1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968513
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN770996
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative
Validations
Cat. No.
ABIN777230
Quantity
96 tests
Datasheet
Datasheet
Recommended MXD1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311686
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311684
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134323
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our MXD1 products
: "The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification." in: Nucleic acids research, Vol. 42, Issue 11, pp. 6901-20, (2014) (PubMed).: "miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the E?-miR-155 transgenic mouse model." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. 20047-52, (2012) (PubMed).
Synonyms and alternative names related to MXD1
MAX dimerization protein 1 (MXD1), MAX dimerization protein 1 (mxd1), MAX dimerization protein 1 L homeolog (mxd1.L), MAX dimerization protein 1 (Mxd1), max dimerization protein 1 (Mxd1), AW122478, BHLHC58, MAD, Mad, Mad-1, MAD1, Mad1, MXD1, si:dkey-202n14.4, xmad1Protein level used designations for MXD1
- MAX dimerization protein 1
- Mad1
- MAD protein
- max dimerization protein 1
- max dimerizer 1
- MAX-binding protein
- antagonizer of myc transcriptional activity
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