MVB12B Products
(Multivesicular Body Subunit 12B (MVB12B))
Categories
The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Featured MVB12B Categories
MVB12B Antibodies
High quality antibodies with extensive validation data.
MVB12B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MVB12B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Guinea Pig, Human
Application
WB
Validations
Cat. No.
ABIN6751612
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN2791520
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC
Validations
Cat. No.
ABIN5938973
Quantity
100 μL
Datasheet
Datasheet
Recommended MVB12B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353443
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3083487
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3123528
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to MVB12B
multivesicular body subunit 12B (MVB12B), multivesicular body subunit 12B (Mvb12b), multivesicular body subunit 12B S homeolog (mvb12b.S), multivesicular body subunit 12Ba (mvb12ba), 2610200O14Rik, 2610528K11Rik, AI414895, C9orf28, FAM125B, Fam125b, fam125b, fam125ba, mvb12b, RGD1309709, zgc:152929Protein level used designations for MVB12B
- ESCRT-I complex subunit MVB12B
- family with sequence similarity 125, member B
- multivesicular body subunit 12B
- uncharacterized protein LOC432218
- family with sequence similarity 125, member B, duplicate a
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