MUS81 Products
(MUS81 Endonuclease Homolog (MUS81))
Categories
Interacts with EME1 and EME2 to form a DNA structure- specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
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Featured MUS81 Categories
MUS81 Antibodies
High quality antibodies with extensive validation data.
MUS81 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MUS81 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7148695
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN6144202
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (2)
Cat. No.
ABIN7262745
Quantity
200 μL
Datasheet
Datasheet
Recommended MUS81 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1798868
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311656
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093974
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our MUS81 products
: "FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice." in: Chromosoma, Vol. 125, Issue 2, pp. 237-52, (2016) (PubMed).: "Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein." in: Nucleic acids research, Vol. 42, Issue 3, pp. 1671-83, (2014) (PubMed).
: "The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy." in: Journal of cell science, Vol. 126, Issue Pt 1, pp. 348-59, (2013) (PubMed).
: "Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN." in: Carcinogenesis, Vol. 33, Issue 9, pp. 1655-63, (2012) (PubMed).
: "CtIP is required to initiate replication-dependent interstrand crosslink repair." in: PLoS genetics, Vol. 8, Issue 11, pp. e1003050, (2012) (PubMed).
: "Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease." in: The Journal of cell biology, Vol. 194, Issue 4, pp. 567-79, (2011) (PubMed).
: "Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes." in: The Journal of cell biology, Vol. 195, Issue 5, pp. 739-49, (2011) (PubMed).
: "SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype." in: Nature genetics, Vol. 43, Issue 2, pp. 138-41, (2011) (PubMed).
: "Mechanism of Holliday junction resolution by the human GEN1 protein." in: Genes & development, Vol. 24, Issue 14, pp. 1559-69, (2010) (PubMed).
: "Telomere recombination requires the MUS81 endonuclease." in: Nature cell biology, Vol. 11, Issue 5, pp. 616-23, (2009) (PubMed).
Synonyms and alternative names related to MUS81
CG3026 gene product from transcript CG3026-RA (mus81), MUS81 structure-specific endonuclease subunit (MUS81), MUS81 structure-specific endonuclease subunit (mus81), crossover junction endonuclease MUS81 (LOC725951), Restriction endonuclease, type II-like superfamily protein (MUS81), Mus81p (MUS81), Holliday junction resolvase subunit Mus81 (mus81), MUS81 protein (mus81), MUS81 structure-specific endonuclease subunit (Mus81), hypothetical protein (CAALFM_C600540WA), 1200008A18Rik, AI182501, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81, ATMUS81, AW045863, CG3026, Dmel\\CG3026, EG:BACR7A4.16, F6I18.220, F6I18_220, GB15332, MMS AND UV SENSITIVE 81, MUS81, SLX3, slx3, wu:fc26g01, zgc:66489, zgc:91801Protein level used designations for MUS81
- CG3026-PA
- mus81-PA
- crossover junction endonuclease MUS81
- MUS81 endonuclease homolog (S. cerevisiae)
- MUS81 endonuclease homolog
- MUS81 protein
- crossover junction endonuclease MUS81-like
- SLX3 structure-specific endonuclease subunit homolog
- hypothetical protein
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