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MUC5B Products

(Mucin 5 Subtype B (MUC5B))
This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010].

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Featured MUC5B Categories

MUC5B Antibodies

High quality antibodies with extensive validation data.

MUC5B ELISA Kits

Reliable ELISA kits for a wide range of species.

MUC5B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MUC5B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7429016
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN7193318
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
Cat. No. ABIN7193568
Quantity 100 μL
Datasheet Datasheet

Recommended MUC5B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957907
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6957906
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957908
Quantity 96 tests
Datasheet Datasheet

Recommended MUC5B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311644
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7505621
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7411138
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MUC5B products

Bianchi, Sivarajan, Walles, Hackenberg, Steinke: "Susceptibility of primary human airway epithelial cells to Bordetella pertussis adenylate cyclase toxin in two- and three-dimensional culture conditions." in: Innate immunity, Vol. 27, Issue 1, pp. 89-98, (2022) (PubMed).

Fang, Uchiyama, Sakai, Hara, Tsutsui, Suda, Mitsuyama, Kawamura, Tsuchiya: "ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism." in: Mucosal immunology, Vol. 12, Issue 5, pp. 1092-1103, (2020) (PubMed).

Pushpass, Pellicciotta, Kelly, Proctor, Carpenter: "Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model." in: Nutrients, Vol. 11, Issue 10, (2019) (PubMed).

Zhang, Derycke, Holtappels, Wang, Zhang, Bachert, Zhang: "Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps." in: Allergy, Vol. 74, Issue 1, pp. 131-140, (2019) (PubMed).

Chaker, Zissler, Poulos, Wagenmann, Bas, Gürth, Xanthou, Schmidt-Weber: "Activin-A Is a Pro-Inflammatory Regulator in Type-2-Driven Upper Airway Disease." in: International archives of allergy and immunology, Vol. 176, Issue 1, pp. 15-25, (2018) (PubMed).

Guan, Zhu, Shen, Jia, Jin, Dong, Xie: "Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling." in: European journal of pharmacology, Vol. 824, pp. 30-39, (2018) (PubMed).

Navarrete, Palacios, Aguilar-Salvatierra, Guardia, Gómez-Moreno: "Effect of Inhaled Corticosteroids on Salival Composition: A Cross-Sectional Study in Patients with Bronchial Asthma." in: Clinical drug investigation, Vol. 35, Issue 9, pp. 569-74, (2015) (PubMed).

Du, Richmond, Blackwell, Cates, Massion, Ware, Lee, Kononov, Lawson, Blackwell, Polosukhin: "Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease." in: Virchows Archiv : an international journal of pathology, Vol. 467, Issue 6, pp. 657-665, (2015) (PubMed).

Sibila, Suarez-Cuartin, Rodrigo-Troyano, Fardon, Finch, Mateus, Garcia-Bellmunt, Castillo, Vidal, Sanchez-Reus, Restrepo, Chalmers: "Secreted mucins and airway bacterial colonization in non-CF bronchiectasis." in: Respirology (Carlton, Vic.), Vol. 20, Issue 7, pp. 1082-8, (2015) (PubMed).

Fields, Song, Rasoul, Fong, Works, Shew, Yiu, Mirsalis, DAndrea: "New candidate biomarkers in the female genital tract to evaluate microbicide toxicity." in: PLoS ONE, Vol. 9, Issue 10, pp. e110980, (2014) (PubMed).

Synonyms and alternative names related to MUC5B

mucin 5B, oligomeric mucus/gel-forming (MUC5B), mucin 5B, oligomeric mucus/gel-forming (Muc5b), ovomucin, alpha subunit (LOC395381), mucin 5AC, oligomeric mucus/gel-forming (MUC5AC), mucin 5B, oligomeric mucus/gel-forming (muc5b), mucin-5B (LOC100498539), mucin 5, subtype B, tracheobronchial (Muc5b), 2300002I04Rik, A130042M24, AV085033, MG1, MUC-5B, MUC5, MUC5B, MUC9, mucin 5b, RGD1561983

Protein level used designations for MUC5B

  • cervical mucin MUC5B
  • high molecular weight salivary mucin MG1
  • mucin 5, subtype B, tracheobronchial
  • mucin-5B
  • sublingual gland mucin
  • ovomucin
  • ovomucin, alpha-subunit
  • mucin 5B, oligomeric mucus/gel-forming
  • mucin protein
  • mucin 5, subtype B, tracheobronchial-like
  • mucin-5B-like
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