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MTRR Products

(5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Featured MTRR Categories

MTRR Antibodies

High quality antibodies with extensive validation data.

MTRR ELISA Kits

Reliable ELISA kits for a wide range of species.

MTRR Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MTRR Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (3)
Cat. No. ABIN7159589
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (1)
Cat. No. ABIN561873
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Chicken, Dog, Human, Monkey, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6745195
Quantity 100 μL
Datasheet Datasheet

Recommended MTRR ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1142322
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1142323
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1142324
Quantity 96 tests
Datasheet Datasheet

Recommended MTRR Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311615
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422505
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422058
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MTRR products

Richard, Desviat, Ugarte, Pérez: "Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects." in: Journal of cellular biochemistry, Vol. 114, Issue 1, pp. 183-91, (2012) (PubMed).

Guise, Abbattista, Tipparaju, Lambie, Su, Li, Wilson, Dachs, Patterson: "Diflavin oxidoreductases activate the bioreductive prodrug PR-104A under hypoxia." in: Molecular pharmacology, Vol. 81, Issue 1, pp. 31-40, (2011) (PubMed).

Synonyms and alternative names related to MTRR

5-methyltetrahydrofolate-homocysteine methyltransferase reductase (Mtrr), 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (mtrr), 4732420G08, cblE, MSR, MTRR

Protein level used designations for MTRR

  • methionine synthase reductase
  • [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing)
  • methionine synthase reductase, mitochondrial
  • 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
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