MTHFD2 Products
(Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))
Categories
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009].
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Featured MTHFD2 Categories
MTHFD2 Antibodies
High quality antibodies with extensive validation data.
MTHFD2 ELISA Kits
Reliable ELISA kits for a wide range of species.
MTHFD2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MTHFD2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (7)
Cat. No.
ABIN7255295
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN6144144
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN564706
Quantity
100 μg
Datasheet
Datasheet
Recommended MTHFD2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968599
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1123843
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1123844
Quantity
96 tests
Datasheet
Datasheet
Recommended MTHFD2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123939
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311558
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2726508
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our MTHFD2 products
: "KRAS mutation status is associated with enhanced dependency on folate metabolism pathways in non-small cell lung cancer cells." in: Molecular cancer therapeutics, Vol. 13, Issue 6, pp. 1611-24, (2014) (PubMed).: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
Synonyms and alternative names related to MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase L homeolog (mthfd2.L), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (mthfd2), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like S homeolog (mthfd2l.S), methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (Mthfd2), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (Mthfd2), AW558851, nmdmc, NMDMC, wu:fb38b11, wu:fe12e11, zgc:91891Protein level used designations for MTHFD2
- bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
- methylene tetrahydrofolate dehydrogenase 2
- methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
- methylenetetrahydrofolate dehydrogenase 2
- NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase
- methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
- methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
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