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MTF1 Products

(Metal-Regulatory Transcription Factor 1 (MTF1))
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008].

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Featured MTF1 Categories

MTF1 Antibodies

High quality antibodies with extensive validation data.

MTF1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MTF1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MTF1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7444628
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN561861
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (2)
Cat. No. ABIN6940090
Quantity 100 μg
Datasheet Datasheet

Recommended MTF1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968563
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1142193
Quantity 96 tests
Datasheet Datasheet

Recommended MTF1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311545
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418620
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418617
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MTF1 products

Zhang, Zhang, Liu, Chen, Li, Ning, Huo, Tian, Ma: "Zn Supplement-Antagonized Cadmium-Induced Cytotoxicity in Macrophages In Vitro: Involvement of Cadmium Bioaccumulation and Metallothioneins Regulation." in: Journal of agricultural and food chemistry, Vol. 67, Issue 16, pp. 4611-4622, (2019) (PubMed).

Fujie, Takenaka, Yoshida, Yasuike, Fujiwara, Shinkai, Kumagai, Yamamoto, Kaji et al.: "Possible mechanisms underlying transcriptional induction of metallothionein isoforms by tris(pentafluorophenyl)stibane, tris(pentafluorophenyl)arsane, and tris(pentafluorophenyl)phosphane in cultured ..." in: The Journal of toxicological sciences, Vol. 44, Issue 5, pp. 327-333, (2019) (PubMed).

Schwarz, Lossow, Kopp, Schwerdtle, Kipp: "Crosstalk of Nrf2 with the Trace Elements Selenium, Iron, Zinc, and Copper." in: Nutrients, Vol. 11, Issue 9, (2019) (PubMed).

Ji, Zhao, Zhang, Huo, Dong, Watari, Jia, Pfeffer, Yue, Zheng: "Knockout of MTF1 Inhibits the Epithelial to Mesenchymal Transition in Ovarian Cancer Cells." in: Journal of Cancer, Vol. 9, Issue 24, pp. 4578-4585, (2018) (PubMed).

Lee, Won, Shin, Kim, Chun: "Reciprocal activation of hypoxia-inducible factor (HIF)-2α and the zinc-ZIP8-MTF1 axis amplifies catabolic signaling in osteoarthritis." in: Osteoarthritis and cartilage, Vol. 24, Issue 1, pp. 134-45, (2015) (PubMed).

Kim, Jeon, Shin, Won, Lee, Kwak, Lee, Rhee, Ryu, Chun, Chun: "Regulation of the catabolic cascade in osteoarthritis by the zinc-ZIP8-MTF1 axis." in: Cell, Vol. 156, Issue 4, pp. 730-43, (2014) (PubMed).

Guo, Lichten, Ryu, Liuzzi, Wang, Cousins: "STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 7, pp. 2818-23, (2010) (PubMed).

Zhang, Meyer, Zhang: "Fetal exposure to cocaine causes programming of Prkce gene repression in the left ventricle of adult rat offspring." in: Biology of reproduction, Vol. 80, Issue 3, pp. 440-8, (2009) (PubMed).

Bellingham, Coleman, Masters, Camakaris, Hill: "Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1." in: The Journal of biological chemistry, Vol. 284, Issue 2, pp. 1291-301, (2009) (PubMed).

Synonyms and alternative names related to MTF1

metal regulatory transcription factor 1 (MTF1), metal-regulatory transcription factor 1 (mtf1), metal-regulatory transcription factor 1 L homeolog (mtf1.L), metal regulatory transcription factor 1 (mtf1), metal response element binding transcription factor 1 (Mtf1), metal-regulatory transcription factor 1 (Mtf1), MGC86485, MTF-1, MTF1, mtf1, Thyls, ZRF

Protein level used designations for MTF1

  • metal regulatory transcription factor 1
  • metal-regulatory transcription factor 1
  • metal regulatory transcription factor 1-like
  • MRE-binding transcription factor
  • metalloregulatory transcription factor
  • transcription factor MTF-1
  • MRE-binding transcription factor-1
  • metal-responsive transcription factor 1
  • zinc regulatory factor
  • metal response element binding transcription factor 1
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