MTA2 Products
(Metastasis Associated 1 Family, Member 2 (MTA2))
Categories
This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011].
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Featured MTA2 Categories
MTA2 Antibodies
High quality antibodies with extensive validation data.
MTA2 ELISA Kits
Reliable ELISA kits for a wide range of species.
MTA2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MTA2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, ChIP
Validations
- (5)
Cat. No.
ABIN7101713
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN390610
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ChIP
Validations
- (3)
Cat. No.
ABIN1680913
Quantity
100 μg
Datasheet
Datasheet
Recommended MTA2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957782
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957783
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5656850
Quantity
96 tests
Datasheet
Datasheet
Recommended MTA2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311518
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311517
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408195
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MTA2 products
: "miR-1236-3p inhibits invasion and metastasis in gastric cancer by targeting MTA2." in: Cancer cell international, Vol. 18, pp. 66, (2018) (PubMed).: "Activation peptide of the coagulation factor XIII (AP-F13A1) as a new biomarker for the screening of colorectal cancer." in: Clinical proteomics, Vol. 15, pp. 15, (2018) (PubMed).
: "Mta2 promotes Tipin-dependent maintenance of replication fork integrity." in: Cell cycle (Georgetown, Tex.), Vol. 13, Issue 13, pp. 2120-8, (2014) (PubMed).
: "Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerases." in: FEBS letters, Vol. 495, Issue 1-2, pp. 1-6, (2001) (PubMed).
Synonyms and alternative names related to MTA2
metastasis associated 1 family member 2 (MTA2), metastasis associated 1 family, member 2 (mta2), metastasis associated 1 family, member 2 (Mta2), metastasis associated 1 family member 2 (mta2), metastasis-associated gene family, member 2 (Mta2), metastasis associated 1 family member 2 L homeolog (mta2.L), metastasis associated 1 family member 2 (Mta2), AW550797, DKFZp470E0911, fd61b05, Mata1l1, mmta2, MTA1L1, mta1l1, Mta1l1, MTA2, PID, pid, wu:fd61b05, wu:fi29g02, zgc:63487Protein level used designations for MTA2
- MTA1-L1 protein
- metastasis -associated gene 1-like 1
- metastasis associated gene family, member 2
- metastasis-associated 1-like 1
- metastasis-associated protein 2
- metastasis-associated protein MTA2
- p53 target protein in deacetylase complex
- metastais-associated gene family, member 2
- metastasis-associated gene family, member 2
- metastasis associated 1 family, member 2
- metastasis-associated protein MTA2-like
- metastasis associated 1-like 1
- metastasis associated 1-like protein
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