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MST1R Products

(Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternatively spliced transcript variants encoding different isoforms with different structural and biochemical properties have been described (PMID:8816464). [provided by RefSeq, Oct 2011].

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Featured MST1R Categories

MST1R Antibodies

High quality antibodies with extensive validation data.

MST1R ELISA Kits

Reliable ELISA kits for a wide range of species.

MST1R Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MST1R Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7440278
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7440248
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN710336
Quantity 100 μL
Datasheet Datasheet

Recommended MST1R ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883840
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730727
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6386118
Quantity 96 tests
Datasheet Datasheet

Recommended MST1R Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6964141
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311483
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509134
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MST1R products

Park, Kim, Kim, Sa, Lee, Yu, Oh, Kim, Yoon, Nam: "Tumor Inhibitory Effect of IRCR201, a Novel Cross-Reactive c-Met Antibody Targeting the PSI Domain." in: International journal of molecular sciences, Vol. 18, Issue 9, (2018) (PubMed).

Sie, den Dunnen, Lourens, Meeuwsen-de Boer, Scherpen, Zomerman, Kampen, Hoving, de Bont: "Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122555, (2015) (PubMed).

Kobayashi, Furukawa, Kikuchi, Ito, Miyata, Muto, Tanaka, Kusano: "Transactivation of RON receptor tyrosine kinase by interaction with PDGF receptor beta during steady-state growth of human mesangial cells." in: Kidney international, Vol. 75, Issue 11, pp. 1173-83, (2009) (PubMed).

Zhang, Yao, Wang: "Activation of RON differentially regulates claudin expression and localization: role of claudin-1 in RON-mediated epithelial cell motility." in: Carcinogenesis, Vol. 29, Issue 3, pp. 552-9, (2008) (PubMed).

Lee, Chen, Chow, Su, Lin, Guo: "Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 6, pp. 2222-8, (2005) (PubMed).

Mallakin, Kutcher, McDowell, Kong, Schuster, Lentsch, Aronow, Leikauf, Waltz: "Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury." in: American journal of respiratory cell and molecular biology, Vol. 34, Issue 1, pp. 15-27, (2005) (PubMed).

Wang, Zhou, Chen: "Macrophage-stimulating protein and RON receptor tyrosine kinase: potential regulators of macrophage inflammatory activities." in: Scandinavian journal of immunology, Vol. 56, Issue 6, pp. 545-53, (2002) (PubMed).

Synonyms and alternative names related to MST1R

macrophage stimulating 1 receptor (MST1R), macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (Mst1r), macrophage stimulating 1 receptor (Mst1r), CD136, CDw136, Cdw136, Fv-2, Fv2, PTK8, Ptk8, RON, Ron, STK, Stk

Protein level used designations for MST1R

  • MSP receptor
  • MST1R variant RON30
  • MST1R variant RON62
  • PTK8 protein tyrosine kinase 8
  • RON variant 21
  • RON variant E2E3
  • c-met-related tyrosine kinase
  • macrophage-stimulating protein receptor
  • p185-Ron
  • soluble RON variant 1
  • soluble RON variant 2
  • soluble RON variant 3
  • soluble RON variant 4
  • friend virus susceptibility 2
  • macrophage-stimulating protein receptor precursor (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase)
  • receptor protein tyrosine kinase, c-met-related
  • stem cell-derived tyrosine kinase
  • protein tyrosine kinase 8
  • tyrosine kinase receptor ron
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