MRVI1 Products
(Murine Retrovirus Integration Site 1 Homolog (MRVI1))
Categories
This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used. [provided by RefSeq, May 2011].
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Featured MRVI1 Categories
MRVI1 Antibodies
High quality antibodies with extensive validation data.
MRVI1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MRVI1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MRVI1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
Cat. No.
ABIN7466656
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit
Application
WB
Validations
Cat. No.
ABIN6753453
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN2773963
Quantity
100 μL
Datasheet
Datasheet
Recommended MRVI1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1151993
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1151994
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1151992
Quantity
96 tests
Datasheet
Datasheet
Recommended MRVI1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2726428
Quantity
20 μg
Datasheet
Datasheet
Synonyms and alternative names related to MRVI1
MRV integration site 1 (Mrvi1), murine retrovirus integration site 1 homolog (MRVI1), BB115629, Irag, IRAG, JAW1L, Ris1Protein level used designations for MRVI1
- JAW1-related protein MRVI1
- inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
- inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate
- murine retrovirus integration site 1 protein
- protein MRVI1
- retroviral integration site 1
- IP3R-associated cGMP kinase substrate
- IP3 receptor associated cGMP kinase substrate
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