MORF4L1 Products
(Mortality Factor 4 Like 1 (MORF4L1))
Categories
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci (By similarity).
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Featured MORF4L1 Categories
MORF4L1 Antibodies
High quality antibodies with extensive validation data.
MORF4L1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MORF4L1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, IHC
Validations
- (6)
Cat. No.
ABIN185075
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (4)
Cat. No.
ABIN2777616
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6263328
Quantity
100 μL
Datasheet
Datasheet
Recommended MORF4L1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6231386
Quantity
96 tests
Datasheet
Datasheet
Recommended MORF4L1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124021
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311164
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311162
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MORF4L1 products
: "Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization." in: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 7092-8, (2014) (PubMed).: "KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription." in: The EMBO journal, Vol. 30, Issue 8, pp. 1473-84, (2011) (PubMed).
: "MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 50860-6, (2002) (PubMed).
Synonyms and alternative names related to MORF4L1
mortality factor 4 like 1 (MORF4L1), mortality factor 4 like 1 (Morf4l1), MORF-related gene 15 (MRG15), MRG15 (CpipJ_CPIJ013367), mortality factor 4 like 1 S homeolog (morf4l1.S), mortality factor 4 like 1 (morf4l1), CG6363, Dmel\\CG6363, DmMRG15, Dmrg15, dMRG15, dMrg15, Eaf3, HsT17725, l(3)j6A3, MEAF3, mKIAA4002, MORF4L2, MORFRG15, MRG15, Mrg15, S863-6, TEG-189, Tex189, zgc:92289Protein level used designations for MORF4L1
- Esa1p-associated factor 3 homolog
- MORF-related gene 15 protein
- MORF-related gene on chromosome 15
- mortality factor 4-like protein 1
- protein MSL3-1
- transcription factor-like protein MRG15
- testis expressed gene 189
- testis-expressed gene 189 protein
- MORF-related gene 15
- mortality factor 4 like 2
- CG6363-PA
- CG6363-PB
- MRG15-PA
- MRG15-PB
- MRG15
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