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MMP3 Products

(Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].

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Featured MMP3 Categories

MMP3 Antibodies

High quality antibodies with extensive validation data.

MMP3 ELISA Kits

Reliable ELISA kits for a wide range of species.

MMP3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MMP3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (6)
Cat. No. ABIN3021709
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7427837
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7431008
Quantity 100 μL
Datasheet Datasheet

Recommended MMP3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (6)
Cat. No. ABIN6730865
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN364941
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6963513
Quantity 96 tests
Datasheet Datasheet

Recommended MMP3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123858
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311086
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311084
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MMP3 products

Chen, Yan, Wu, Yao, Sun, Pang, Fu: "Injectable bio-responsive hydrogel for therapy of inflammation related eyelid diseases." in: Bioactive materials, Vol. 6, Issue 10, pp. 3062-3073, (2021) (PubMed).

Luo, Huan, Lin, Kong, Sun, Li, Zhu, Sun, Xu, Sun, Duan, Shi: "Ulinastatin Ameliorates IL-1β-Induced Cell Dysfunction in Human Nucleus Pulposus Cells via Nrf2/NF-κB Pathway." in: Oxidative medicine and cellular longevity, Vol. 2021, pp. 5558687, (2021) (PubMed).

Wu, Chen, Huang, Pan, Chen, Zhang, Lin, Liu, Wu: "Electroacupuncture Delays Cartilage Degeneration by Modulating Nuclear Factor-κB Signaling Pathway." in: Chinese journal of integrative medicine, Vol. 25, Issue 9, pp. 677-683, (2020) (PubMed).

Li, Zeng: "Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis." in: World journal of pediatrics : WJP, Vol. 16, Issue 5, pp. 502-513, (2020) (PubMed).

Mirastschijski, Lupše, Maedler, Sarma, Radtke, Belge, Dorsch, Wedekind, McCawley, Boehm, Zier, Yamamoto, Kelm, Ågren: "Matrix Metalloproteinase-3 is Key Effector of TNF-α-Induced Collagen Degradation in Skin." in: International journal of molecular sciences, Vol. 20, Issue 20, (2020) (PubMed).

Szóstek-Mioduchowska, Słowińska, Pacewicz, Skarzynski, Okuda: "Matrix metallopeptidase expression and modulation by transforming growth factor-β1 in equine endometrosis." in: Scientific reports, Vol. 10, Issue 1, pp. 1119, (2020) (PubMed).

Gao, Wang, Wu: "Teneligliptin inhibits IL-1β-induced degradation of extracellular matrix in human chondrocytes." in: Journal of cellular biochemistry, Vol. 121, Issue 11, pp. 4450-4457, (2020) (PubMed).

Chen, Zhao, Ma, Chen, Wu, Zhu, Zhu, Ma, Zhao: "Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis via the MAPK/ERK Pathway." in: Frontiers in pharmacology, Vol. 11, pp. 527744, (2020) (PubMed).

Mirastschijski, Dinesh, Baskaran, Wedekind, Gavrilovic, Murray, Bevan, Kelm: "Novel specific human and mouse stromelysin-1 (MMP-3) and stromelysin-2 (MMP-10) antibodies for biochemical and immunohistochemical analyses." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, Vol. 27, Issue 4, pp. 309-323, (2019) (PubMed).

Zhuo, Li, Zhang: "Activation of G-protein-coupled bile acid receptor Gpbar1 (TGR5) inhibits degradation of type II collagen and aggrecan in human chondrocytes." in: European journal of pharmacology, Vol. 856, pp. 172387, (2019) (PubMed).

Synonyms and alternative names related to MMP3

matrix metallopeptidase 3 (MMP3), matrix metallopeptidase 3 (Mmp3), matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3), matrix metallopeptidase 3 L homeolog (mmp3.L), CHDS6, chds6, MMP-3, mmp-3, mmp3, MMP10, mmp13, SL-1, sl-1, SLN-1, SLN1, STMY, stmy, STMY1, Stmy1, stmy1, STR-1, STR1, Str1, str1

Protein level used designations for MMP3

  • matrix metalloproteinase 3 (stromelysin 1, progelatinase)
  • matrix metalloproteinase-3
  • proteoglycanase
  • stromelysin-1
  • transin-1
  • EMS-2
  • MMP-3
  • SL-1
  • matrix metalloproteinase 3
  • progelatinase
  • stromelysin 1
  • PTR1 protein
  • stromelysin
  • metalloproteinase 3 receptor
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • matrix metallopeptidase 3 L homeolog
  • matrix metalloproteinase 13 (collagenase 3)
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