MMP25 Products
(Matrix Metallopeptidase 25 (MMP25))
Categories
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq, Jul 2008].
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Featured MMP25 Categories
MMP25 Antibodies
High quality antibodies with extensive validation data.
MMP25 ELISA Kits
Reliable ELISA kits for a wide range of species.
MMP25 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MMP25 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7268422
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (5)
Cat. No.
ABIN7258762
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7242293
Quantity
200 μL
Datasheet
Datasheet
Recommended MMP25 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957696
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN5069263
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5656751
Quantity
96 tests
Datasheet
Datasheet
Recommended MMP25 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7395290
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN6120491
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MMP25 products
: "Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25)." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 35023-32, (2008) (PubMed).: "MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties." in: The Journal of biological chemistry, Vol. 282, Issue 30, pp. 21998-2010, (2007) (PubMed).
: "Clusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36350-7, (2003) (PubMed).
: "Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors." in: Cancer research, Vol. 60, Issue 4, pp. 877-82, (2000) (PubMed).
Synonyms and alternative names related to MMP25
matrix metallopeptidase 25 (MMP25), matrix metallopeptidase 25 (Mmp25), F730048C11Rik, Leukolysin, MMP-25, MMP20, MMP20A, MMPL1, MT-MMP 6, MT-MMP6, MT6-MMP, MT6MMP, MTMMP6Protein level used designations for MMP25
- leukolysin
- matrix metallopeptidase-like 1
- matrix metalloproteinase 20
- matrix metalloproteinase 25
- matrix metalloproteinase-25
- matrix metalloproteinase-like 1
- membrane-type 6 matrix metalloproteinase
- membrane-type matrix metalloproteinase 6
- membrane-type-6 matrix metalloproteinase
- MMP-25
- LOW QUALITY PROTEIN: matrix metalloproteinase-25
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