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MMP13 Products

(Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Categories

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].

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Featured MMP13 Categories

MMP13 Antibodies

High quality antibodies with extensive validation data.

MMP13 ELISA Kits

Reliable ELISA kits for a wide range of species.

MMP13 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MMP13 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
  • (7)
  • (6)
Cat. No. ABIN670341
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7430978
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ICC, IHC (p), IHC (fro)
Validations
  • (1)
  • (5)
Cat. No. ABIN2854829
Quantity 100 μL
Datasheet Datasheet

Recommended MMP13 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (5)
Cat. No. ABIN6730928
Quantity 96 tests
Datasheet Datasheet
Reactivity Rabbit
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (6)
Cat. No. ABIN6720554
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (5)
Cat. No. ABIN6730863
Quantity 96 tests
Datasheet Datasheet

Recommended MMP13 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7490699
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7490727
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123854
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our MMP13 products

Xiao, Li, Zhang, Xu, Zhang: "Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritis." in: Cell biology international, Vol. 47, Issue 7, pp. 1183-1197, (2023) (PubMed).

Dai, Lu, Li, Yang, Ji, Wang: "Changes in cartilage and subchondral bone in a growing rabbit experimental model of developmental trochlear dysplasia of the knee." in: Connective tissue research, Vol. 62, Issue 3, pp. 299-312, (2022) (PubMed).

Bai, Zhang, Fan, Xu, Shan, Gao, Ma, Sheng, Zheng, Cheng, Li, Zhang, Hao, Feng, Chen, Zhou, Wang: "Reactive Oxygen Species-Scavenging Scaffold with Rapamycin for Treatment of Intervertebral Disk Degeneration." in: Advanced healthcare materials, Vol. 9, Issue 3, pp. e1901186, (2021) (PubMed).

Momma, Onodera, Homan, Matsubara, Sasazawa, Furukawa, Matsuoka, Yamashita, Iwasaki: "Coordinated existence of multiple gangliosides is required for cartilage metabolism." in: Osteoarthritis and cartilage, Vol. 27, Issue 2, pp. 314-325, (2020) (PubMed).

Wauquier, Mevel, Krisa, Richard, Valls, Hornedo-Ortega, Granel, Boutin-Wittrant, Urban, Berger, Descamps, Guicheux, Vinatier, Beck, Meunier, Blot, Wittrant: "Chondroprotective Properties of Human-Enriched Serum Following Polyphenol Extract Absorption: Results from an Exploratory Clinical Trial." in: Nutrients, Vol. 11, Issue 12, (2020) (PubMed).

Chen, Che, Han, Lu, Wang, Liang, Hou, Wei, Wei, Li: "MicroRNA-1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post-transcriptional suppression of Ihh expression." in: Molecular medicine reports, Vol. 22, Issue 3, pp. 2404-2414, (2020) (PubMed).

Pitrez, Estronca, Monteiro, Colell, Vazão, Santinha, Harhouri, Thornton, Navarro, Egesipe, Carvalho, Dos Santos, Lévy, Smith, de Magalhães, Ori, Bernardo, De Sandre-Giovannoli, Nissan, Rosell et al.: "Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13. ..." in: Nature communications, Vol. 11, Issue 1, pp. 4110, (2020) (PubMed).

Gundogdu, Demirkaya Miloglu, Gundogdu, Tasci, Albayrak, Demirci, Cetin: "Investigation of the efficacy of daidzein in experimental knee osteoarthritis-induced with monosodium iodoacetate in rats." in: Clinical rheumatology, Vol. 39, Issue 8, pp. 2399-2408, (2020) (PubMed).

Shen, Sun, Nie, Yuan, Cai, Wu, Hu, Jin, Zhou, Zhang, He: "Sulindac-derived retinoid X receptor-α modulator attenuates atherosclerotic plaque progression and destabilization in ApoE-/- mice." in: British journal of pharmacology, Vol. 176, Issue 14, pp. 2559-2572, (2019) (PubMed).

Nakagawa, Lebaschi, Wada, Green, Wang, Album, Carballo, Deng, Rodeo: "Duration of postoperative immobilization affects MMP activity at the healing graft-bone interface: Evaluation in a mouse ACL reconstruction model." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 37, Issue 2, pp. 325-334, (2019) (PubMed).

Synonyms and alternative names related to MMP13

matrix metallopeptidase 13 (MMP13), matrix metallopeptidase 13 (Mmp13), matrix metallopeptidase 13a (mmp13a), matrix metallopeptidase 13 (collagenase 3) like S homeolog (mmp13l.S), matrix metallopeptidase 13 (collagenase 3) (mmp13), matrix metalloproteinase 13 (LOC100136348), matrix metalloproteinase 13 (mmp13), matrix metallopeptidase 13 (mmp13), matrix metallopeptidase 13 (collagenase 3) like L homeolog (mmp13l.L), cb1034, Clg, CLG3, gene A, MANDP1, MGC108008, MMP-13, Mmp1, mmp13, MMP13, xcl3, xCol

Protein level used designations for MMP13

  • MMP-13
  • collagenase 3
  • matrix metalloproteinase 13 (collagenase 3)
  • Collagenase-3
  • collagenase-1
  • interstitial collagenase
  • matrix metalloproteinase 13
  • matrix metalloproteinase-13
  • UMRCASE
  • collagenase-3
  • MMPLg
  • MMPLh
  • gene 11
  • matrix metallopeptidase 13 (collagenase 3)
  • gene A
  • collagenase 3-like
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