MLLT11 Products
(Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
Categories
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1\;11)(q21\;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008].
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Featured MLLT11 Categories
MLLT11 Antibodies
High quality antibodies with extensive validation data.
MLLT11 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MLLT11 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (5)
- (2)
Cat. No.
ABIN564754
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (2)
Cat. No.
ABIN1387553
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (2)
Cat. No.
ABIN7074715
Quantity
100 μL
Datasheet
Datasheet
Recommended MLLT11 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124041
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311017
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5853757
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MLLT11 products
: "MLLT11/AF1q is differentially expressed in maturing neurons during development." in: Gene expression patterns : GEP, Vol. 15, Issue 2, pp. 80-7, (2014) (PubMed).: "AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells." in: PLoS ONE, Vol. 7, Issue 6, pp. e39968, (2012) (PubMed).
: "AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway." in: Blood, Vol. 118, Issue 7, pp. 1784-96, (2011) (PubMed).
: "Identification of the functional role of AF1Q in the progression of breast cancer." in: Breast cancer research and treatment, Vol. 111, Issue 1, pp. 65-78, (2008) (PubMed).
: "Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway." in: Molecular cancer therapeutics, Vol. 7, Issue 10, pp. 3160-8, (2008) (PubMed).
Synonyms and alternative names related to MLLT11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (MLLT11), MLLT11, transcription factor 7 cofactor (MLLT11), myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (Mllt11), MLLT11, transcription factor 7 cofactor (Mllt11), MLLT11, transcription factor 7 cofactor (mllt11), AF1Q, Af1q, AI839562, fc23g02, RGD1305525, RP11-316M1.10, si:ch211-210h11.4, wu:fc23g02, Zfp692Protein level used designations for MLLT11
- protein AF1q
- ALL1 fused gene from chromosome 1q
- ALL1-fused gene from chromosome 1q
- zinc finger protein 692
- AF1Q protein
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