MLL4 Products
(Histone-Lysine N-Methyltransferase MLL4 (MLL4))
Categories
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008].
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Featured MLL4 Categories
MLL4 Antibodies
High quality antibodies with extensive validation data.
MLL4 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended MLL4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN564215
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IHC (p)
Validations
Cat. No.
ABIN6388423
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
Cat. No.
ABIN5620182
Quantity
100 μL
Datasheet
Datasheet
Recommended MLL4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503557
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503558
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503559
Quantity
96 tests
Datasheet
Datasheet
Recommended MLL4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN7509078
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MLL4 products
: "Targeting the MLL complex in castration-resistant prostate cancer. ..." in: Nature medicine, Vol. 21, Issue 4, pp. 344-52, (2015) (PubMed).: "MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines." in: Oncogene, Vol. 18, Issue 56, pp. 7975-84, (2000) (PubMed).
Synonyms and alternative names related to MLL4
lysine methyltransferase 2B (KMT2B), lysine (K)-specific methyltransferase 2B (Kmt2b), lysine (K)-specific methyltransferase 2D (Kmt2d), lysine methyltransferase 2B (Kmt2b), 2610014H22Rik, ALR, BC032281, BC058659, C430014K11Rik, HRX2, KMT2B, mKIAA0304, MLL1B, MLL2, Mll2, MLL4, Mll4, RGD1308331, TRX2, WBP7, Wbp7Protein level used designations for MLL4
- KMT2D
- WBP-7
- WW domain binding protein 7
- WW domain-binding protein 7
- histone-lysine N-methyltransferase 2B
- histone-lysine N-methyltransferase MLL4
- lysine N-methyltransferase 2B
- lysine N-methyltransferase 2D
- mixed lineage leukemia gene homolog 2
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4
- myeloid/lymphoid or mixed-lineage leukemia 4
- myeloid/lymphoid or mixed-lineage leukemia protein 4
- trithorax homolog 2
- trithorax homologue 2
- mixed lineage leukemia 2
- myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog
- ALL1-related protein
- histone-lysine N-methyltransferase 2D
- histone-lysine N-methyltransferase MLL2
- myeloid/lymphoid or mixed-lineage leukemia 2
- myeloid/lymphoid or mixed-lineage leukemia protein 2
- LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B
- histone-lysine N-methyltransferase 2B-like
- lysine (K)-specific methyltransferase 2B
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