MLL2 Products
(Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))
Categories
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008].
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Featured MLL2 Categories
MLL2 Antibodies
High quality antibodies with extensive validation data.
MLL2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended MLL2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC (p), WB
Validations
- (3)
- (3)
Cat. No.
ABIN6243263
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
- (1)
Cat. No.
ABIN948660
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IHC
Validations
- (2)
Cat. No.
ABIN1494780
Quantity
50 μg
Datasheet
Datasheet
Recommended MLL2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503544
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503545
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503546
Quantity
96 tests
Datasheet
Datasheet
Recommended MLL2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311012
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MLL2 products
: "Molecular analysis, pathogenic mechanisms, and readthrough therapy on a large cohort of Kabuki syndrome patients. ..." in: Human mutation, Vol. 35, Issue 7, pp. 841-50, (2014) (PubMed).: "UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells." in: Cancer research, Vol. 74, Issue 6, pp. 1705-17, (2014) (PubMed).
: "Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo." in: The Journal of steroid biochemistry and molecular biology, Vol. 141, pp. 160-70, (2014) (PubMed).
: "Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4." in: Genes & development, Vol. 26, Issue 24, pp. 2749-62, (2012) (PubMed).
Synonyms and alternative names related to MLL2
lysine methyltransferase 2D (KMT2D), lysine methyltransferase 2B (KMT2B), lysine (K)-specific methyltransferase 2D (Kmt2d), myeloid/lymphoid or mixed-lineage leukemia 2 (MLL2), lysine methyltransferase 2D (Kmt2d), AAD10, ALR, BC032281, BC058659, C430014K11Rik, CAGL114, HRX2, KABUK1, KMS, KMT2B, MLL1B, MLL2, Mll2, MLL4, Mll4, TNRC21, TRX2, WBP7Protein level used designations for MLL2
- ALL1-related protein
- Kabuki make-up syndrome
- Kabuki mental retardation syndrome
- histone-lysine N-methyltransferase 2D
- histone-lysine N-methyltransferase MLL2
- lysine N-methyltransferase 2D
- myeloid/lymphoid or mixed-lineage leukemia 2
- trinucleotide repeat containing 21
- KMT2D
- WBP-7
- WW domain binding protein 7
- WW domain-binding protein 7
- histone-lysine N-methyltransferase 2B
- histone-lysine N-methyltransferase MLL4
- lysine N-methyltransferase 2B
- mixed lineage leukemia gene homolog 2
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4
- myeloid/lymphoid or mixed-lineage leukemia 4
- myeloid/lymphoid or mixed-lineage leukemia protein 4
- trithorax homolog 2
- trithorax homologue 2
- myeloid/lymphoid or mixed-lineage leukemia protein 2
- LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2D
- lysine (K)-specific methyltransferase 2D
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