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MLL/KMT2A Proteins

(Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010].

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MLL/KMT2A Protein (AA 3735-3973) (GST tag) (ABIN6579161)

MLL Origin: Human Host: Escherichia coli (E. coli) Recombinant EAA, ScA

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MLL/KMT2A Proteins by Origin

Find MLL/KMT2A Proteins for a variety of species such as anti-Human MLL/KMT2A. The species listed below are among those available. Click on a link to go to the corresponding products.

MLL/KMT2A Proteins by Source

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MLL/KMT2A Proteins by Protein Type

Here you can find MLL/KMT2A Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

MLL/KMT2A Proteins by Application

Find MLL/KMT2A Proteins validated for a specific application such as EAA, ScA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MLL/KMT2A Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

MLL/KMT2A Protein (AA 3735-3973) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6579161

Quantity 50 μg

Datasheet Datasheet

Aliases for MLL/KMT2A Proteins

lysine methyltransferase 2A (KMT2A) Proteins
lysine (K)-specific methyltransferase 2A (Kmt2a) Proteins
lysine methyltransferase 2A (Kmt2a) Proteins
6430520K01 Proteins
ALL-1 Proteins
All1 Proteins
CXXC7 Proteins
Cxxc7 Proteins
HRX Proteins
HTRX1 Proteins
mKIAA4050 Proteins
MLL Proteins
Mll Proteins
MLL/GAS7 Proteins
Mll1 Proteins
MLL1A Proteins
TET1-MLL Proteins
TRX1 Proteins
WDSTS Proteins

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