MKL1 Products
(Megakaryoblastic Leukemia (Translocation) 1 (MKL1))
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The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq, Jul 2008].
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Featured MKL1 Categories
MKL1 Antibodies
High quality antibodies with extensive validation data.
Recommended MKL1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (3)
Cat. No.
ABIN6143855
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN1387286
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6259116
Quantity
100 μL
Datasheet
Datasheet
Recommended MKL1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968520
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our MKL1 products
: "Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas." in: Nature medicine, Vol. 24, Issue 3, pp. 271-281, (2018) (PubMed).: "Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices." in: Scientific reports, Vol. 5, pp. 11458, (2015) (PubMed).
: "Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1." in: Blood, Vol. 126, Issue 13, pp. 1527-35, (2015) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "RhoA as a mediator of clinically relevant androgen action in prostate cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 5, pp. 716-35, (2012) (PubMed).
: "The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1." in: Oncogene, Vol. 31, Issue 35, pp. 3913-23, (2012) (PubMed).
Synonyms and alternative names related to MKL1
megakaryoblastic leukemia (translocation) 1 (MKL1), megakaryoblastic leukemia 1 protein (mkl1), megakaryoblastic leukemia (translocation) 1 (Mkl1), megakaryoblastic leukemia (translocation) 1 S homeolog (mkl1.S), MKL (megakaryoblastic leukemia)/myocardin-like 1 (Mkl1), AI852829, AMKL, AW743281, AW821984, BSAC, Bsac, MAL, Mal, MKL1, MRTF-A, Mrtf-a, mrtf-a, Mrtf-A, mrtfaProtein level used designations for MKL1
- megakaryoblastic leukemia 1 protein
- MKL/myocardin-like protein 1
- RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein
- basic, SAP and coiled-coil domain
- megakaryocytic acute leukemia protein
- myocardin-related transcription factor A
- xMRTF-A
- basic SAP and coiled-coil domains
- basic SAP coiled-coil transcription activator
- megakaryoblastic leukemia (translocation) 1 homolog
- megakaryoblastic leukemia 1 protein homolog
Did you look for something else?
- MKL
- MKKS
- MK13
- MK03
- MIXL1
- Mitogen-Activated Protein Kinase Kinase Kinase 3
- Mitogen-Activated Protein Kinase Kinase Kinase 13
- Mitogen-Activated Protein Kinase Kinase 4
- Mitogen-Activated Protein Kinase Kinase 2
- Mitogen-Activated Protein Kinase 1
- Mitogen-Activated Protein Kinase
- Mitochondrially Encoded NADH Dehydrogenase 4
- Mitochondrially Encoded ATP Synthase 8
- Mitochondrial Translation Elongation Factor EF-Ts Tsf1
- Mitochondrial Import Receptor Subunit TOM20 homolog
- Mitochondrial E3 Ubiquitin Protein Ligase 1
- Mitochondrial ATPase Subunit 8
- MITF
- MITD1
- Mismatch Repair Protein 2
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