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MITF Products

(Microphthalmia-Associated Transcription Factor (MITF))

Categories

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured MITF Categories

MITF Antibodies

High quality antibodies with extensive validation data.

MITF ELISA Kits

Reliable ELISA kits for a wide range of species.

MITF Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MITF Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IF (p)
Validations
  • (4)
  • (8)
Cat. No. ABIN676373
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, IHC, IF, ELISA, ICC
Validations
  • (10)
Cat. No. ABIN6255037
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (1)
  • (5)
Cat. No. ABIN655506
Quantity 400 μL
Datasheet Datasheet

Recommended MITF ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957807
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968606
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN579092
Quantity 96 tests
Datasheet Datasheet

Recommended MITF Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123955
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310958
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409062
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MITF products

Lin, Izar, Wang, Yapp, Mei, Shah, Santagata, Sorger: "Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes." in: eLife, Vol. 7, (2019) (PubMed).

Rice, Cebra-Thomas, Haugas, Partanen, Rice, Gilbert: "Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta." in: Scientific reports, Vol. 7, Issue 1, pp. 12063, (2019) (PubMed).

Zhang, Yue, Jiang, Wang, Liu: "Identification of an MITF gene and its polymorphisms associated with the Vibrio resistance trait in the clam Meretrix petechialis." in: Fish & shellfish immunology, Vol. 68, pp. 466-473, (2018) (PubMed).

Zhang, Wang, Yu, Jiang, Yue, Liu: "Identification of a gene encoding microphthalmia-associated transcription factor and its association with shell color in the clam Meretrix petechialis." in: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, Vol. 225, pp. 75-83, (2018) (PubMed).

Kito, Saigo, Takeuchi: "Novel Transgenic Mouse Model of Polycystic Kidney Disease." in: The American journal of pathology, Vol. 187, Issue 9, pp. 1916-1922, (2017) (PubMed).

Ishii, Ryu, Suzuki: "Lactoferrin inhibits melanogenesis by down-regulating MITF in melanoma cells and normal melanocytes." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 95, Issue 1, pp. 119-125, (2017) (PubMed).

Han, Sung, Lee: "Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells." in: Journal of food science, Vol. 81, Issue 8, pp. H2085-92, (2016) (PubMed).

Ursini, Cavalleri, Fazio, Angrisano, Iacovelli, Porcelli, Maddalena, Punzi, Mancini, Gelao, Romano, Masellis, Calabrese, Rampino, Taurisano, Di Giorgio, Keller, Tarantini, Sinibaldi, Quarto et al.: "BDNF rs6265 methylation and genotype interact on risk for schizophrenia. ..." in: Epigenetics, Vol. 11, Issue 1, pp. 11-23, (2016) (PubMed).

Gehlsen, Szaszák, Gebert, Koop, Hüttmann, Steven: "Non-Invasive Multi-Dimensional Two-Photon Microscopy enables optical fingerprinting (TPOF) of immune cells." in: Journal of biophotonics, Vol. 8, Issue 6, pp. 466-79, (2016) (PubMed).

Otreba, Wrze?niok, Beberok, Rok, Buszman: "Melanogenesis and antioxidant defense system in normal human melanocytes cultured in the presence of chlorpromazine." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 29, Issue 1, pp. 221-7, (2015) (PubMed).

Synonyms and alternative names related to MITF

melanogenesis associated transcription factor (MITF), microphthalmia-associated transcription factor (mitf), microphthalmia-associated transcription factor (LOC100313655), microphthalmia-associated transcription factor S homeolog (mitf.S), microphthalmia-associated transcription factor (LOC100534525), Microphthalmia (MICROP), microphthalmia-associated transcription factor (Mitf), melanogenesis associated transcription factor (Mitf), BCC2, bHLHe32, Bhlhe32, bw, CMI9, CMM8, Gsfbcc2, LOC100313655, MI, mi, MITF, MITF-A, MITF-H, MITF-M, mitfa, mitfb, vit, Vitiligo, Wh, WS2, ws2a, WS2A

Protein level used designations for MITF

  • microphthalmia transcription factor
  • microphthalmia-associated transcription factor
  • micophthalmia-associated transcription factor b
  • class E basic helix-loop-helix protein 32
  • black eyed white
  • transcription factor
  • microphtalmia-associated transcription factor
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