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Minichromosome Maintenance Complex Component 5 Products

(Minichromosome Maintenance Complex Component 5 (MCM5))
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008].

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Featured Minichromosome Maintenance Complex Component 5 Categories

Minichromosome Maintenance Complex Component 5 Antibodies

High quality antibodies with extensive validation data.

Minichromosome Maintenance Complex Component 5 ELISA Kits

Reliable ELISA kits for a wide range of species.

Minichromosome Maintenance Complex Component 5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Minichromosome Maintenance Complex Component 5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (6)
Cat. No. ABIN6263163
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (8)
Cat. No. ABIN7257096
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (5)
Cat. No. ABIN6143644
Quantity 100 μL
Datasheet Datasheet

Recommended Minichromosome Maintenance Complex Component 5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957842
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381303
Quantity 96 tests
Datasheet Datasheet

Recommended Minichromosome Maintenance Complex Component 5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1310557
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505292
Quantity 100 μg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2854011
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Minichromosome Maintenance Complex Component 5 products

Panneerselvam, Pickering, Han, Li, Zheng, Zhang, Zhang, Fei: "Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate." in: Oncotarget, Vol. 5, Issue 5, pp. 1326-37, (2014) (PubMed).

Hubbi, Gilkes, Hu, Kshitiz, Ahmed, Semenza: "Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 32, pp. E3325-34, (2014) (PubMed).

Hubbi, Kshitiz, Gilkes, Rey, Wong, Luo, Kim, Dang, Levchenko, Semenza: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).

Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).

Hubbi, Luo, Baek, Semenza: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).

Yan, Michael: "TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks." in: The Journal of cell biology, Vol. 184, Issue 6, pp. 793-804, (2009) (PubMed).

Adams, Medhurst, Dart, Lakin: "Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex." in: Oncogene, Vol. 25, Issue 28, pp. 3894-904, (2006) (PubMed).

Yan, Lindsay, Michael: "Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling." in: The Journal of cell biology, Vol. 173, Issue 2, pp. 181-6, (2006) (PubMed).

Dart, Adams, Akerman, Lakin: "Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase." in: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 16433-40, (2004) (PubMed).

Forsburg: "Eukaryotic MCM proteins: beyond replication initiation." in: Microbiology and molecular biology reviews : MMBR, Vol. 68, Issue 1, pp. 109-31, (2004) (PubMed).

Synonyms and alternative names related to Minichromosome Maintenance Complex Component 5

DNA replication licensing factor MCM5 (BBOV_IV010040), minichromosome maintenance complex component 5 S homeolog (mcm5.S), minichromosome maintenance complex component 5 (MCM5), DNA replication licensing factor Mcm5 (AFUA_5G02520), DNA replication licensing factor mcm5 (NCU01171), DNA replication licensing factor MCM5 (PVX_084615), DNA replication licensing factor Mcm5 (LOC5576119), DNA replication licensing factor mcm5 (CpipJ_CPIJ008678), DNA replication licensing factor MCM5 (Bm1_24480), DNA replication licensing factor MCM5 (CMU_022890), minichromosome maintenance complex component 5 (Mcm5), minichromosome maintenance complex component 5 (mcm5), DNA replication licensing factor MCM5 (TP01_0722), MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) (mcm5), minichromosome maintenance complex component 5 L homeolog (mcm5.L), Minichromosome maintenance 5 (Mcm5), DNA replication licensing factor mcm-5 (mcm-5), 23.m06024, AA617332, Afu5g02520, AI324988, AL033333, cdc46, CDC46, Cdc46, CG4082, DmCDC46, DmCDC465, Dmel\\CG4082, DmeMCM5, DmMCM5, DmMcm5, mCD46, mCDC46, mcm5, MCM5, McM5, Mcmd5, NCU01171.1, P1-CDC46, PCR4, wu:fb34a06, xmcm5

Protein level used designations for Minichromosome Maintenance Complex Component 5

  • DNA replication licensing factor mcm5-B
  • xMCM5-B
  • xCDC46-B
  • CDC46 homolog B
  • CDC46 homolog
  • DNA replication licensing factor MCM5
  • MCM5 minichromosome maintenance deficient 5, cell division cycle 46
  • minichromosome maintenance deficient 5 (cell division cycle 46)
  • DNA replication licensing factor mcm5
  • mini chromosome maintenance deficient 5
  • minichromosome maintenance deficient 5, cell division cycle 46
  • minichromosome maintenance deficient protein 5
  • CDC46 homolog A
  • CDC46p
  • DNA replication licensing factor mcm5-A
  • p92
  • xCDC46-A
  • xMCM5-A
  • CG4082-PA
  • Mcm5-PA
  • mini-chromosome maintenance 5
  • minichromosome maintenance 5
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