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MID1 Products

(Midline 1 (MID1))
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing\; however, the full-length nature of some of the variants has not been determined. [provided by RefSeq, Jul 2010].

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Featured MID1 Categories

MID1 Antibodies

High quality antibodies with extensive validation data.

MID1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MID1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MID1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6265724
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7188874
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7151071
Quantity 100 μL
Datasheet Datasheet

Recommended MID1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957836
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648016
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5656907
Quantity 96 tests
Datasheet Datasheet

Recommended MID1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310921
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413310
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3074726
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MID1 products

Bell, Malyukova, Holien, Koach, Parker, Kavallaris, Marshall, Cheung: "TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members." in: PLoS ONE, Vol. 7, Issue 5, pp. e37470, (2012) (PubMed).

Liu, Knutzen, Krauss, Schweiger, Chiang: "Control of mTORC1 signaling by the Opitz syndrome protein MID1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 21, pp. 8680-5, (2011) (PubMed).

Synonyms and alternative names related to MID1

midline 1 (MID1), midline 1 (Mid1), midline 1 (mid1), midline 1 L homeolog (mid1.L), 61B3-R, BBBG1, bbbg1, DXHXS1141, FXY, Fxy, fxy, GBBB1, gbbb1, MIDIN, midin, Midline1, OGS1, ogs1, OS, OSX, osx, RNF59, rnf59, TRIM18, Trim18, trim18, XPRF, xprf, ZNFXY, znfxy

Protein level used designations for MID1

  • RING finger protein 59
  • midline 1 RING finger protein
  • midline-1
  • putative transcription factor XPRF
  • tripartite motif protein TRIM18
  • tripartite motif-containing protein 18
  • zinc finger on X and Y, mouse, homolog of
  • midin
  • Finger on X and Y (in rat only on X)
  • E3 ubiquitin-protein ligase Midline-1
  • midline 1 (Opitz/BBB syndrome)
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