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MIB2 Products

(E3 ubiquitin-protein ligase MIB2 (MIB2))
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).

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Featured MIB2 Categories

MIB2 Antibodies

High quality antibodies with extensive validation data.

MIB2 ELISA Kits

Reliable ELISA kits for a wide range of species.

MIB2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MIB2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7439483
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7439507
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN530831
Quantity 200 μL
Datasheet Datasheet

Recommended MIB2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1131158
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1131159
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1131160
Quantity 96 tests
Datasheet Datasheet

Recommended MIB2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310905
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405400
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405451
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MIB2 products

Piccolo, Attanasio, Secco, Sangermano, Strisciuglio, Limongelli, Miele, Mutarelli, Banfi, Nigro, Pons, Valencia, Zentilin, Campione, Nardone, Lynnes, Celestino-Soper, Spoonamore, DArmiento, Giacca et al.: "MIB2 variants altering NOTCH signalling result in left ventricle hypertrabeculation/non-compaction and are associated with Ménétrier-like gastropathy. ..." in: Human molecular genetics, Vol. 26, Issue 1, pp. 33-43, (2016) (PubMed).

Stempin, Chi, Giraldo-Vela, High, Häcker, Redecke: "The E3 ubiquitin ligase mind bomb-2 (MIB2) protein controls B-cell CLL/lymphoma 10 (BCL10)-dependent NF-κB activation." in: The Journal of biological chemistry, Vol. 286, Issue 43, pp. 37147-57, (2011) (PubMed).

Jurd, Thornton, Wang, Luong, Phamluong, Kharazia, Gibb, Ron: "Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner." in: The Journal of biological chemistry, Vol. 283, Issue 1, pp. 301-10, (2007) (PubMed).

Synonyms and alternative names related to MIB2

mindbomb E3 ubiquitin protein ligase 2 (MIB2), mindbomb E3 ubiquitin protein ligase 2 (Mib2), mindbomb E3 ubiquitin protein ligase 2 (mib2), mindbomb E3 ubiquitin protein ligase 2 S homeolog (mib2.S), 2210008I11Rik, mib2, skd, ZZANK1, Zzank1, ZZZ5

Protein level used designations for MIB2

  • E3 ubiquitin-protein ligase MIB2
  • mind bomb homolog 2
  • mindbomb homolog 2
  • novel zinc finger protein
  • novelzin
  • putative NF-kappa-B-activating protein 002N
  • skeletrophin
  • zinc finger ZZ type with ankyrin repeat domain protein 1
  • zinc finger, ZZ type with ankyrin repeat domain 1
  • dyslike
  • dystrophin-like protein
  • mind bomb-2
  • RBSC-skeletrophin
  • RBSC-skeletrophin/dystrophin-like polypeptide
  • miblike
  • mindbomb E3 ubiquitin protein ligase 2 S homeolog
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