MIB1 Products
(Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
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Featured MIB1 Categories
MIB1 Antibodies
High quality antibodies with extensive validation data.
MIB1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MIB1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey
Application
ELISA, WB, IHC, ICC, FACS
Validations
- (5)
Cat. No.
ABIN5542434
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7151063
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN388956
Quantity
400 μL
Datasheet
Datasheet
Recommended MIB1 ELISA Kits
Recommended MIB1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310903
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2725966
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7405397
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MIB1 products
: "Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA." in: Cell reports, Vol. 25, Issue 13, pp. 3811-3827.e7, (2018) (PubMed).: "The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein." in: Molecular biology of the cell, Vol. 24, Issue 12, pp. 1863-71, (2013) (PubMed).
: "Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods." in: The EMBO journal, Vol. 30, Issue 8, pp. 1520-35, (2011) (PubMed).
: "Notch signalling: a simple pathway becomes complex." in: Nature reviews. Molecular cell biology, Vol. 7, Issue 9, pp. 678-89, (2006) (PubMed).
: "Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta." in: Developmental cell, Vol. 4, Issue 1, pp. 67-82, (2003) (PubMed).
: "A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 46980-6, (2002) (PubMed).
Synonyms and alternative names related to MIB1
mindbomb E3 ubiquitin protein ligase 1 (MIB1), mindbomb E3 ubiquitin protein ligase 1 (Mib1), mindbomb E3 ubiquitin protein ligase 1 L homeolog (mib1.L), mindbomb E3 ubiquitin protein ligase 1 (mib1), mind bomb 1 (mib1), cg5841, CG5841, chunp6889, D-mib, D-mib1, DIP-1, dip-1, DIP1, Dmel\CG5841, Dmib, dmib1, E430019M12Rik, fe47f05, im:7148100, l(3)72CDa, l(3)72Db, LVNC7, MIB, Mib, mib, mib1, MIB1, Mib1, mib1/2, mind-bomb, mindbomb, mKIAA1323, wu:fe47f05, ZZANK2, ZZZ6Protein level used designations for MIB1
- DAPK-interacting protein 1
- E3 ubiquitin-protein ligase MIB1
- ubiquitin ligase mind bomb
- zinc finger ZZ type with ankyrin repeat domain protein 2
- DAPK-interacting protein-1
- mind bomb homolog 1
- mind bomb-1
- skeletrophin
- E3 ubiquitin-protein ligase mib1
- mind bomb
- mindbomb homolog 1
- protein mind bomb
- white tail
- wit
- CG5841 gene product from transcript CG5841-RA
- CG5841-PA
- CG5841-PB
- Mind bomb homolog
- Mindbomb1
- RING-type E3 ubiquitin transferase mind-bomb
- lethal (3) 72CDa
- lethal (3) 72Db
- mib1-PA
- mib1-PB
- mind bomb1
- mind-bomb
- mindbomb
- mindbomb 1
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