MGLL Products
(Monoglyceride Lipase (MGLL))
Categories
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].
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Featured MGLL Categories
MGLL Antibodies
High quality antibodies with extensive validation data.
MGLL ELISA Kits
Reliable ELISA kits for a wide range of species.
MGLL Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MGLL Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, FACS, IF
Validations
- (9)
Cat. No.
ABIN334436
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN2855646
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7160192
Quantity
100 μL
Datasheet
Datasheet
Recommended MGLL ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968668
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957875
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975648
Quantity
96 tests
Datasheet
Datasheet
Recommended MGLL Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1310880
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124018
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7279205
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MGLL products
: "Hemisphere-dependent endocannabinoid system activity in prefrontal cortex and hippocampus of the Flinders Sensitive Line rodent model of depression." in: Neurochemistry international, Vol. 125, pp. 7-15, (2019) (PubMed).: "Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11)." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 93, pp. 253-63, (2016) (PubMed).
: "YAP-mediated induction of monoacylglycerol lipase restrains oncogenic transformation." in: Cellular signalling, Vol. 27, Issue 4, pp. 836-40, (2015) (PubMed).
: "The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 24, pp. E2472-81, (2014) (PubMed).
: "Mutation of Cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency." in: Molecular pharmacology, Vol. 85, Issue 3, pp. 510-9, (2014) (PubMed).
: "Robust hydrolysis of prostaglandin glycerol esters by human monoacylglycerol lipase (MAGL)." in: Molecular pharmacology, Vol. 86, Issue 5, pp. 522-35, (2014) (PubMed).
: "Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)." in: Journal of lipid research, Vol. 53, Issue 11, pp. 2413-24, (2012) (PubMed).
: "The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation." in: Journal of lipid research, Vol. 52, Issue 5, pp. 958-70, (2011) (PubMed).
: "A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol." in: Chemistry & biology, Vol. 14, Issue 12, pp. 1347-56, (2007) (PubMed).
Synonyms and alternative names related to MGLL
monoglyceride lipase (mgll), monoglyceride lipase (MGLL), monoglyceride lipase L homeolog (mgll.L), 13L protein (13L), monoglyceride lipase (YMTVg13L), Monoglyceride lipase (EHI_044210), Monoglyceride lipase (EHI_045330), monoglyceride lipase (TATV_DAH68_039), monoglyceride lipase (13L), monoglyceride lipase (Mgll), AA589436, cb909, hu-k5, HU-K5, HUK5, MAGL, Magl, MGC84195, mgl, MGL, Mgl, MGLL, mgll, wu:fc66g01, zgc:56561Protein level used designations for MGLL
- monoglyceride lipase
- Monoglyceride lipase
- lysophospholipase homolog
- monoacylglycerol lipase
- MGL
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