MFN2 Products
(Mitofusin 2 (MFN2))
Categories
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
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Featured MFN2 Categories
MFN2 Antibodies
High quality antibodies with extensive validation data.
MFN2 ELISA Kits
Reliable ELISA kits for a wide range of species.
MFN2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MFN2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), RNAi
Validations
- (8)
- (7)
Cat. No.
ABIN564263
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rabbit, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (2)
- (5)
Cat. No.
ABIN682528
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN6143800
Quantity
100 μL
Datasheet
Datasheet
Recommended MFN2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6968636
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957855
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN435454
Quantity
96 tests
Datasheet
Datasheet
Recommended MFN2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310805
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2726078
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505289
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MFN2 products
: "A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities." in: Frontiers in cell and developmental biology, Vol. 10, pp. 1000553, (2022) (PubMed).: "Maternal serum mitofusin-2 levels in patients with preeclampsia: the possible role of mitochondrial dysfunction in preeclampsia." in: The journal of maternal-fetal & neonatal medicine, pp. 1-6, (2019) (PubMed).
: "Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3-dependent manner." in: British journal of pharmacology, Vol. 175, Issue 8, pp. 1126-1145, (2018) (PubMed).
: "Downregulation of mitochondrial cyclooxygenase-2 inhibits the stemness of nasopharyngeal carcinoma by decreasing the activity of dynamin-related protein 1." in: Theranostics, Vol. 7, Issue 5, pp. 1389-1406, (2018) (PubMed).
: "Enhancement of Mitochondrial Transfer by Antioxidants in Human Mesenchymal Stem Cells." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 8510805, (2018) (PubMed).
: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).
: "Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device." in: BMC cancer, Vol. 17, Issue 1, pp. 234, (2017) (PubMed).
: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." in: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).
: "Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation." in: Scientific reports, Vol. 6, pp. 23464, (2016) (PubMed).
: "Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).
Synonyms and alternative names related to MFN2
mitofusin 2 (MFN2), Mitochondrial assembly regulatory factor (Marf), mitofusin 2 (mfn2), mitofusin-2 (LOC100186475), mitofusin 2 (Mfn2), mitofusin 2 L homeolog (mfn2.L), anon-WO0125274.3, CG3869, cmt2a, CMT2A, cmt2a2, CMT2A2, cprp1, CPRP1, D630023P19Rik, Dmel\\CG3869, dMFN, dMfn, dmfn, Fzo, hsg, HSG, MARF, marf, Marf-1, Mfn, mfn, mfn2, MFN2, mg:cb01g09, si:dkeyp-104h9.2, wu:fb79a11Protein level used designations for MFN2
- CG3869-PA
- CG3869-PB
- CG3869-PC
- Marf-PA
- Marf-PB
- Marf-PC
- drosophila mitofusin
- mitochondrial assembly regulatory factor
- mitofusin
- mitofusin 2
- mitofusin-2
- mitofusin-2-like
- hyperplasia suppressor
- transmembrane GTPase MFN2
- HSG protein
- hypertension related protein 1
- hypertension-related protein 1
- hypertension-related protein
- mitochondrial transmembrane GTPase FZO1A
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