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METTL3 Products

(Methyltransferase Like 3 (METTL3))

Categories

This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008].

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Featured METTL3 Categories

METTL3 Antibodies

High quality antibodies with extensive validation data.

METTL3 ELISA Kits

Reliable ELISA kits for a wide range of species.

METTL3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended METTL3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (6)
Cat. No. ABIN7264399
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (2)
  • (5)
Cat. No. ABIN6143771
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (3)
Cat. No. ABIN1327559
Quantity 50 μg
Datasheet Datasheet

Recommended METTL3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1144033
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1144034
Quantity 96 tests
Datasheet Datasheet

Recommended METTL3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123947
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310760
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2725892
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our METTL3 products

Liang, Guan, Lin, Li, Geng, Li: "METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway." in: Oncology letters, Vol. 19, Issue 4, pp. 3197-3204, (2020) (PubMed).

Xiang, Yang, Liu, Wu, Chen, Yang: "N6-Methyladenosines Modulate A-to-I RNA Editing." in: Molecular cell, Vol. 69, Issue 1, pp. 126-135.e6, (2018) (PubMed).

Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

Ping, Sun, Wang, Xiao, Yang, Wang, Adhikari, Shi, Lv, Chen, Zhao, Li, Yang, Dahal, Lou, Liu, Huang, Yuan, Zhu, Cheng, Zhao, Wang, Rendtlew Danielsen, Liu, Yang: "Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase." in: Cell research, Vol. 24, Issue 2, pp. 177-89, (2014) (PubMed).

Dominissini, Moshitch-Moshkovitz, Schwartz, Salmon-Divon, Ungar, Osenberg, Cesarkas, Jacob-Hirsch, Amariglio, Kupiec, Sorek, Rechavi: "Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq." in: Nature, Vol. 485, Issue 7397, pp. 201-6, (2012) (PubMed).

Ginkel, Wordeman: "Expression and partial characterization of kinesin-related proteins in differentiating and adult skeletal muscle." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4143-58, (2000) (PubMed).

Yamazaki, Nakata, Okada, Hirokawa: "Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8443-8, (1996) (PubMed).

Synonyms and alternative names related to METTL3

methyltransferase like 3 (mettl3), methyltransferase like 3 L homeolog (mettl3.L), methyltransferase like 3 (METTL3), methyltransferase like 3 (Mettl3), methyltransferase-like 3 (Mettl3), 2310024F18Rik, fj82g07, IME4, M6A, MT-A70, Spo8, wu:fj82g07, zgc:77093

Protein level used designations for METTL3

  • N6-adenosine-methyltransferase 70 kDa subunit
  • adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase
  • mRNA m(6)A methyltransferase
  • methyltransferase-like protein 3
  • MT-A70
  • m6a methyltransferase
  • methyltransferase-like 3
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