Metalloproteinase Inhibitor 2 Products
(Metalloproteinase Inhibitor 2 (TIMP2))
Categories
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008].
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Featured Metalloproteinase Inhibitor 2 Categories
Metalloproteinase Inhibitor 2 Antibodies
High quality antibodies with extensive validation data.
Metalloproteinase Inhibitor 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Metalloproteinase Inhibitor 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Metalloproteinase Inhibitor 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (7)
Cat. No.
ABIN1513608
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (7)
Cat. No.
ABIN948564
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p), FACS
Validations
- (12)
Cat. No.
ABIN1501393
Quantity
100 μL
Datasheet
Datasheet
Recommended Metalloproteinase Inhibitor 2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6957768
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6957770
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
- (1)
Cat. No.
ABIN6957767
Quantity
96 tests
Datasheet
Datasheet
Recommended Metalloproteinase Inhibitor 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275737
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275741
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322790
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Metalloproteinase Inhibitor 2 products
: "The MiR-495/Annexin A3/P53 Axis Inhibits the Invasion and EMT of Colorectal Cancer Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 5, pp. 1882-1895, (2018) (PubMed).: "The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway." in: Scientific reports, Vol. 6, pp. 29975, (2018) (PubMed).
: "High glucose stimulates cell proliferation and Collagen IV production in rat mesangial cells through inhibiting AMPK-KATP signaling." in: International urology and nephrology, Vol. 49, Issue 11, pp. 2079-2086, (2018) (PubMed).
: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "Triptonide inhibits the pathological functions of gastric cancer-associated fibroblasts." in: Biomedicine & pharmacotherapy, Vol. 96, pp. 757-767, (2018) (PubMed).
: "The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis." in: International journal of biological macromolecules, Vol. 103, pp. 1000-1010, (2017) (PubMed).
: "Effect of Novel Gasotransmitter hydrogen sulfide on renal fibrosis and connexins expression in diabetic rats." in: Bioengineered, Vol. 7, Issue 5, pp. 314-320, (2017) (PubMed).
: "Erratum: Long-term intravenous administration of carboxylated single-walled carbon nanotubes induces persistent accumulation in the lungs and pulmonary fibrosis via the nuclear factor-kappa B pathway ..." in: International journal of nanomedicine, Vol. 12, pp. 1515, (2017) (PubMed).
: "Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 25, Issue 3, pp. 715-727, (2017) (PubMed).
: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." in: International wound journal, (2016) (PubMed).
Synonyms and alternative names related to Metalloproteinase Inhibitor 2
TIMP metallopeptidase inhibitor 2 (TIMP2), TIMP metallopeptidase inhibitor 2b (timp2b), TIMP metallopeptidase inhibitor 2 (Timp2), tissue inhibitor of metalloproteinase 2 (Timp2), TIMP metallopeptidase inhibitor 2a (timp2a), TIMP metallopeptidase inhibitor 2 L homeolog (timp2.L), CSC-21K, D11Bwg1104e, DDC8, etID32613.12, fa96h09, Timp-2, TIMP-2, timp2, timp2l, wu:fa96h09, zgc:65967, zgc:85799, zgc:136726Protein level used designations for Metalloproteinase Inhibitor 2
- TIMP-2
- metalloproteinase inhibitor 2
- tissue inhibitor of metalloproteinase 2
- tissue inhibitor of metalloproteinases 2
- tissue inhibitor of metalloproteinase 2, like
- tissue inhibitor of matrix metalloproteinase-2
- tissue inhibitor of metalloproteinase-2
- collagenase inhibitor
- tissue inhibitor of mettaloproteinase 2
- metalloproteinase inhibitor TIMP-2
- TIMP metallopeptidase inhibitor 2 L homeolog
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