Metabotropic Glutamate Receptor 4 Products
(Glutamate Receptor, Metabotropic 4 (GRM4))
Categories
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
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Featured Metabotropic Glutamate Receptor 4 Categories
Metabotropic Glutamate Receptor 4 Antibodies
High quality antibodies with extensive validation data.
Metabotropic Glutamate Receptor 4 ELISA Kits
Reliable ELISA kits for a wide range of species.
Metabotropic Glutamate Receptor 4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Metabotropic Glutamate Receptor 4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6261989
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Pig, Rabbit
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1048935
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7185130
Quantity
100 μg
Datasheet
Datasheet
Recommended Metabotropic Glutamate Receptor 4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381314
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1743302
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1774207
Quantity
96 tests
Datasheet
Datasheet
Recommended Metabotropic Glutamate Receptor 4 Proteins
Latest Publications for our Metabotropic Glutamate Receptor 4 products
: "Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells." in: Oncogene, Vol. 23, Issue 4, pp. 945-55, (2004) (PubMed).: "Methylation analysis of the glypican 3 gene in embryonal tumours." in: British journal of cancer, Vol. 90, Issue 8, pp. 1606-11, (2004) (PubMed).
: "Identification of glypican-3 as a novel tumor marker for melanoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 19, pp. 6612-21, (2004) (PubMed).
Synonyms and alternative names related to Metabotropic Glutamate Receptor 4
glutamate metabotropic receptor 4 (GRM4), glutamate receptor, metabotropic 4 (Grm4), glutamate metabotropic receptor 4 (Grm4), glutamate receptor, metabotropic 4 (GRM4), GPRC1D, Gprc1d, mGlu4, MGLUR4, mGluR4Protein level used designations for Metabotropic Glutamate Receptor 4
- metabotropic glutamate receptor 4
- G protein-coupled receptor GRM4
- G protein-coupled receptor, family C, group 1, member D
- mGluR4
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