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MEF2D Products

(Myocyte Enhancer Factor 2D (MEF2D))

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This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

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Featured MEF2D Categories

MEF2D Antibodies

High quality antibodies with extensive validation data.

MEF2D Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MEF2D Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7160506
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN517838
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN517841
Quantity 100 μg
Datasheet Datasheet

Recommended MEF2D ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648635
Quantity 96 tests
Datasheet Datasheet

Recommended MEF2D Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124047
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310694
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310696
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MEF2D products

Okamoto, Li, Ju, Scholzke, Mathews, Cui, Salvesen, Bossy-Wetzel, Lipton: "Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 6, pp. 3974-9, (2002) (PubMed).

Guttridge, Mayo, Madrid, Wang, Baldwin: "NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia." in: Science (New York, N.Y.), Vol. 289, Issue 5488, pp. 2363-6, (2000) (PubMed).

Mora, Pessin: "The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive GLUT4 glucose transporter." in: The Journal of biological chemistry, Vol. 275, Issue 21, pp. 16323-8, (2000) (PubMed).

Kato, Zhao, Morikawa, Sugiyama, Chakravortty, Koide, Yoshida, Tapping, Yang, Yokochi, Lee: "Big mitogen-activated kinase regulates multiple members of the MEF2 protein family." in: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18534-40, (2000) (PubMed).

Zhao, New, Kravchenko, Kato, Gram, di Padova, Olson, Ulevitch, Han: "Regulation of the MEF2 family of transcription factors by p38." in: Molecular and cellular biology, Vol. 19, Issue 1, pp. 21-30, (1999) (PubMed).

Breitbart, Liang, Smoot, Laheru, Mahdavi, Nadal-Ginard: "A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage." in: Development (Cambridge, England), Vol. 118, Issue 4, pp. 1095-106, (1994) (PubMed).

Martin, Miano, Hustad, Copeland, Jenkins, Olson: "A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing." in: Molecular and cellular biology, Vol. 14, Issue 3, pp. 1647-56, (1994) (PubMed).

Synonyms and alternative names related to MEF2D

myocyte enhancer factor 2D (mef2d), myocyte enhancer factor 2D (MEF2D), MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) (MEF2D), myocyte enhancer factor 2D (Mef2d), C80750, MGC145245, sl-1, sl1, XMEF2D

Protein level used designations for MEF2D

  • myocyte enhancer factor 2D
  • MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)
  • myocyte-specific enhancer factor 2D-like
  • MADS box transcription enhancer factor 2, polypeptide D
  • myocyte-specific enhancer factor 2D
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