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MEF2C Products

(Myocyte Enhancer Factor 2C (MEF2C))

Categories

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010].

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Featured MEF2C Categories

MEF2C Antibodies

High quality antibodies with extensive validation data.

MEF2C ELISA Kits

Reliable ELISA kits for a wide range of species.

MEF2C Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MEF2C Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (7)
Cat. No. ABIN1098145
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p), ICC, IHC (fro), IP
Validations
  • (1)
  • (4)
Cat. No. ABIN2856105
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (4)
Cat. No. ABIN7260573
Quantity 200 μL
Datasheet Datasheet

Recommended MEF2C ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380846
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648633
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883753
Quantity 96 tests
Datasheet Datasheet

Recommended MEF2C Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124046
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310692
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505290
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MEF2C products

Zhang, Zhang, Nam: "Stoichiometric optimization of Gata4, Hand2, Mef2c, and Tbx5 expression for contractile cardiomyocyte reprogramming." in: Scientific reports, Vol. 9, Issue 1, pp. 14970, (2019) (PubMed).

Brown, Still, Koche, Yim, Takao, Cifani, Reed, Gunasekera, Ficarro, Romanienko, Mark, McCarthy, de Stanchina, Gonen, Seshan, Bhola, ODonnell, Spitzer, Stutzke, Lavallée, Hébert, Krivtsov, Melnick et al.: "MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia. ..." in: Cancer discovery, Vol. 8, Issue 4, pp. 478-497, (2019) (PubMed).

Deczkowska, Matcovitch-Natan, Tsitsou-Kampeli, Ben-Hamo, Dvir-Szternfeld, Spinrad, Singer, David, Winter, Smith, Kertser, Baruch, Rosenzweig, Terem, Prinz, Villeda, Citri, Amit, Schwartz: "Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner." in: Nature communications, Vol. 8, Issue 1, pp. 717, (2018) (PubMed).

Law, Leung, Yau, Tse, Wong, Leung, Mascheck, Huang, Sauer, Tsang et al.: "Regulation of multiple transcription factors by reactive oxygen species and effects of pro-inflammatory cytokines released during myocardial infarction on cardiac differentiation of embryonic stem ..." in: International journal of cardiology, Vol. 168, Issue 4, pp. 3458-72, (2013) (PubMed).

Clark, Zhang, Lee, Evans, Lassar, Lee: "Evolutionary conservation of Nkx2.5 autoregulation in the second heart field." in: Developmental biology, Vol. 374, Issue 1, pp. 198-209, (2013) (PubMed).

Lockhart, Wirrig, Phelps, Ghatnekar, Barth, Norris, Wessels: "Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart." in: PLoS ONE, Vol. 8, Issue 2, pp. e57073, (2013) (PubMed).

Inagawa, Miyamoto, Yamakawa, Muraoka, Sadahiro, Umei, Wada, Katsumata, Kaneda, Nakade, Kurihara, Obata, Miyake, Fukuda, Ieda: "Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5." in: Circulation research, Vol. 111, Issue 9, pp. 1147-56, (2012) (PubMed).

Xu, Cao, Wang, Xu, Chen, Xu: "VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C." in: PLoS ONE, Vol. 6, Issue 11, pp. e27165, (2011) (PubMed).

Stephens, Stephens, Hobbs, Hutmacher, Bacic-Welsh, Woodruff, Morrison: "Myocyte enhancer factor 2c, an osteoblast transcription factor identified by dimethyl sulfoxide (DMSO)-enhanced mineralization." in: The Journal of biological chemistry, Vol. 286, Issue 34, pp. 30071-86, (2011) (PubMed).

Escher, Schorderet, Cottet: "Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice." in: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5933-40, (2011) (PubMed).

Synonyms and alternative names related to MEF2C

myocyte enhancer factor 2C (MEF2C), MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) (mef2c), myocyte enhancer factor 2cb (mef2cb), MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) L homeolog (mef2c.L), myocyte enhancer factor 2C (Mef2c), myocyte enhancer factor 2ca (mef2ca), 5430401D19Rik, 9930028G15Rik, AV011172, C5DELq14.3, DEL5q14.3, id:ibd5026, Mef2, MEF2C, mef2c, RGD1563119, si:ch211-202e12.2, wu:fc05b06, XMEF2C, zgc:64184, zgc:85726

Protein level used designations for MEF2C

  • myocyte-specific enhancer factor 2C
  • myocyte enhancer factor 2C
  • myocyte-specific enhancer factor 2C-like
  • MADS box transcription enhancer factor 2, polypeptide C
  • MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)
  • Myocyte enhancer factor 2C protein
  • hoo
  • hoover
  • myocyte enhancer factor 2c
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