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MED13 Products

(Mediator Complex Subunit 13 (MED13))
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008].

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Featured MED13 Categories

MED13 Antibodies

High quality antibodies with extensive validation data.

MED13 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended MED13 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7191442
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
Cat. No. ABIN7188319
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
Cat. No. ABIN6283989
Quantity 50 μL
Datasheet Datasheet

Recommended MED13 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743271
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774176
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1744490
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our MED13 products

Wagner, DeLuca: "Temporal association of herpes simplex virus ICP4 with cellular complexes functioning at multiple steps in PolII transcription." in: PLoS ONE, Vol. 8, Issue 10, pp. e78242, (2013) (PubMed).

Zhou, Spaeth, Kim, Xu, Friez, Schwartz, Boyer: "MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 48, pp. 19763-8, (2012) (PubMed).

Knuesel, Meyer, Donner, Espinosa, Taatjes: "The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator." in: Molecular and cellular biology, Vol. 29, Issue 3, pp. 650-61, (2009) (PubMed).

Synonyms and alternative names related to MED13

mediator complex subunit 13 (MED13), mediator complex subunit 13 (Med13), mediator complex subunit 13b (med13b), 1110067M05Rik, ARC250, D030023K18, DRIP250, HSPC221, med13, skuld-like, THRAP1, Thrap1, TRAP240, Trap240, wu:fb66c06, wu:fc43h07, wu:fc43h08, zgc:153454

Protein level used designations for MED13

  • activator-recruited cofactor 250 kDa component
  • mediator of RNA polymerase II transcription subunit 13
  • mediator of RNA polymerase II transcription, subunit 13 homolog
  • thyroid hormone receptor associated protein 1
  • thyroid hormone receptor-associated protein 1
  • thyroid hormone receptor-associated protein complex 240 kDa component
  • thyroid hormone receptor-associated protein complex component TRAP240
  • thyroid hormone receptor-associated protein, 240 kDa subunit
  • vitamin D3 receptor-interacting protein complex component DRIP250
  • Zmediator complex subunit 13
  • mediator of RNA polymerase II transcription, subunit 13
  • thyroid hormone receptor associated protein, 240 kDa subunit
  • mediator complex subunit 13
  • fc43h07
  • fc43h08
  • mediator of RNA polymerase II transcription subunit 13-like
  • thyroid hormone receptor-associated protein complex 240 kDa component-like protein
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